N6-methyladenosine links RNA metabolism to cancer progression

D Dai, H Wang, L Zhu, H Jin, X Wang - Cell death & disease, 2018 - nature.com
Abstract N6-methyladenosine (m6A) is the most abundant mRNA modification. With the
development of antibody-based sequencing technologies and the findings of m6A-related …

Role of m6A writers, erasers and readers in cancer

Z Fang, W Mei, C Qu, J Lu, L Shang, F Cao… - … Hematology & Oncology, 2022 - Springer
Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

[HTML][HTML] The role of m6A RNA methylation in cancer

T Sun, R Wu, L Ming - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract N6-methyladenosine (m6A), the most abundant internal modification of RNA in
eukaryotic cells, has gained increasing attention in recent years. The m6A modification …

Diverse molecular functions of m6A mRNA modification in cancer

SH Han, J Choe - Experimental & molecular medicine, 2020 - nature.com
Abstract N 6-methyladenosine (m6A), the most prevalent chemical modification found on
eukaryotic mRNA, is associated with almost all stages of mRNA metabolism and influences …

Aberrant Regulation of mRNA m6A Modification in Cancer Development

J Luo, H Liu, S Luan, C He, Z Li - International journal of molecular …, 2018 - mdpi.com
N 6-methyladenosine (m6A) is the most prevalent internal modification of eukaryotic
messenger RNAs (mRNAs). The m6A modification in RNA can be catalyzed by …

N6‐methyladenosine Steers RNA Metabolism and Regulation in Cancer

S Dong, Y Wu, Y Liu, H Weng… - Cancer …, 2021 - Wiley Online Library
As one of the most studied ribonucleic acid (RNA) modifications in eukaryotes, N6‐
methyladenosine (m6A) has been shown to play a predominant role in controlling gene …

RNA m6A modification in cancers: molecular mechanisms and potential clinical applications

C Gu, X Shi, C Dai, F Shen, G Rocco, J Chen, Z Huang… - The innovation, 2020 - cell.com
N 6-Methyladenosine (m 6 A) RNA modification brings a new dawn for RNA modification
researches in recent years. This posttranscriptional RNA modification is dynamic and …

[HTML][HTML] N6-Methyladenosine modification: a novel pharmacological target for anti-cancer drug development

Y Niu, A Wan, Z Lin, X Lu, G Wan - Acta pharmaceutica sinica B, 2018 - Elsevier
Abstract N 6-Methyladenosine (m 6 A) modification is the most pervasive modification of
human mRNA molecules. It is reversible via regulation of m 6 A modification …

Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer

Y Chen, Y Lin, Y Shu, J He, W Gao - Molecular cancer, 2020 - Springer
As a critical internal RNA modification in higher eukaryotes, N 6-methyladenosine (m 6 A)
has become the hotspot of epigenetics research in recent years. Extensive studies on …

[HTML][HTML] The emerging molecular mechanism of m6A modulators in tumorigenesis and cancer progression

S Liu, Q Li, K Chen, Q Zhang, G Li, L Zhuo… - Biomedicine & …, 2020 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is the most abundant RNA modification; m 6 A
modifications are installed by methyltransferases, removed by demethylases and …