Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …

Myocardial infarction (MI) is a major source of morbidity and mortality worldwide, with over 7
million people suffering infarctions each year. Heart muscle damaged during MI is replaced …

The mechanical properties of the healing scar are an important determinant of heart function
following myocardial infarction. Yet the relationship between scar structure, scar mechanics …

During healing after myocardial infarction, scar collagen content and stiffness do not
correlate. We studied regional mechanics and both area fraction and orientation of large …

Infarct scar tissue has long been considered inert (acellular, composed simply of fibrillar
collagen) and whose function is simply to restore structural integrity to infarcted myocardium …

Cardiac scars, often dubbed 'dead tissue', are very much alive, with heterocellular activity
contributing to the maintenance of structural and mechanical integrity following heart injury …

Infarct scar, a requisite to the rebuilding of necrotic myocardium following myocardial
infarction (MI), has long been considered inert. Earlier morphologic studies suggested …

Key points• After myocardial infarction, fibroblasts infiltrate the necrotic myocardium, deposit
collagen, and remodel collagen, forming scar tissue.• Mechanical, structural, and chemical …

Objectives: This study was designed to compare electroanatomic mapping (EAM) and
magnetic resonance imaging (MRI) with delayed contrast enhancement (DCE) data for …

After myocardial infarction, remodeling of the left ventricle involves a wound-healing
orchestra involving a variety of cell types. In order for wound healing to be optimal …