Dose‐response to salbutamol via a novel palm sized nebuliser (Aerodose® Inhaler), conventional nebuliser (Pari LC Plus) and metered dose inhaler (Ventolin™ …

BJ Lipworth, EJ Sims, K Taylor… - British journal of …, 2005 - Wiley Online Library
Aims The Aerodose® inhaler is a novel, palm‐sized, breath actuated device which requires
little patient coordination. This study compared the dose–response of salbutamol delivered …

Nebuliser performance, pharmacokinetics, airways and systemic effects of salbutamol given via a novel nebuliser delivery system (" Ventstream").

DM Newnham, BJ Lipworth - Thorax, 1994 - thorax.bmj.com
BACKGROUND--Currently available nebulisers are inefficient and show variable aerosol
deposition in the lung owing to the differences in the particle size generated. The aim of this …

Differing bioavailability of salbutamol metered-dose inhalers

SK Chhabra - Journal of Asthma, 1987 - Taylor & Francis
The bronchodilator efficacy of two brands of salbutamol (USAN albuterol) metered-dose
inhalers (MDIs) was compared in a double-blind protocol involving 31 asthmatics. Specific …

[HTML][HTML] Comparison of bronchodilator responses of levosalbutamol and salbutamol given via a pressurized metered dose inhaler: a randomized, double blind, single …

A Jantikar, B Brashier, M Maganji, A Raghupathy… - Respiratory …, 2007 - Elsevier
BACKGROUND: Salbutamol, the most widely used short-acting β2-agonist, consists of a
racemic mixture of equal amounts of two enantiomers,(R)-salbutamol and (S)-salbutamol …

Equivalence of as-required salbutamol propelled by propellants 11 and 12 or HFA 134a in mild to moderate asthmatics

CR Baumgarten, P Dorow, HH Weber, R Gebhardt… - Respiratory …, 2000 - Elsevier
This randomized, double-blind, parallel-group study compared the efficacy and tolerability of
as-required salbutamol 100μg administered from either a chlorofluorocarbon (CFC) …

Cumulative dose-response study of non-CFC propellant HFA 134a salbutamol sulfate metered-dose inhaler in patients with asthma

EC Kleerup, DP Tashkin, AC Cline, BP Ekholm - Chest, 1996 - Elsevier
Study objective This study compares the safety and efficacy of HFA 134a salbutamol sulfate
(Airomir in the 3M CFC-free system [3M Pharmaceuticals]) and CFC 11/12 salbutamol …

Bronchodilating effects of salbutamol from a novel inhaler AirmaxTM

MV Middle, J Terblanché, VL Perrin, MGL Hertog - Respiratory medicine, 2002 - Elsevier
This randomized, placebo-controlled, evaluator-blind, five-way crossover study compared
the equivalence in terms of FEV1 response to single ascending cumulative doses of …

A critical comparison of the dose delivery characteristics of four alternative inhalation devices delivering salbutamol: pressurized metered dose inhaler, Diskus inhaler …

D Prime, AC Grant, AL Slater… - Journal of aerosol …, 1999 - liebertpub.com
Salbutamol is a short-acting β2 agonist which is effective as a rescue therapy in the
treatment of asthma. This study uses in vitro test methods to compare the capability of four …

[HTML][HTML] An aerosol formulation of R-salbutamol sulfate for pulmonary inhalation

X Zhang, Q Liu, J Hu, L Xu, W Tan - Acta Pharmaceutica Sinica B, 2014 - Elsevier
An aerosol formulation containing 7.5 mg of R-salbutamol sulfate was developed. The
aerosol was nebulized with an air-jet nebulizer, and further assessed according to the new …

Salbutamol relative lung and systemic bioavailability of large and small spacers

SHRA Mazhar, H Chrystyn - Journal of Pharmacy and …, 2008 - Wiley Online Library
Differences between the size and shape of spacers may affect the emitted dose and provide
different effects when interchanged during routine use. Using a urinary pharmacokinetic …