Background: We tested our hypothesis that the white matter network might mediate the effect
of amyloid and small vessel disease (SVD) on cortical thickness and/or cognition. Methods …

There is growing evidence that the human brain is a large scale complex network. The
structural network is reported to be disrupted in cognitively impaired patients. However …

Objective To determine whether longitudinal change in white matter structural network
integrity predicts dementia and future cognitive decline in cerebral small vessel disease …

To determine whether white matter network disruption mediates the association between
MRI markers of cerebrovascular disease (CeVD) and cognitive impairment. Participants (n …

Objective: To examine the relation between measures of whole-brain white matter
connectivity and cognitive performance in patients with early Alzheimer disease (AD) using …

Objective: To examine whether structural network connectivity at baseline predicts incident
all-cause dementia in a prospective hospital-based cohort of elderly participants with MRI …

Cerebral small vessel disease (SVD) is a common disease in older adults and a major
contributor to vascular cognitive impairment and dementia. White matter network damage is …

Central brain network connections greatly contribute to overall network efficiency. Here we
examined whether small vessel disease (SVD) related white matter alterations in central …

Cerebral small vessel disease (SVD), including white matter hyperintensities (WMH),
lacunes and microbleeds, and brain atrophy, are related to cognitive impairment. However …

Background and purpose Mechanisms underlying cognitive impairment in patients with
small vessel disease (SVD) are still unknown. We hypothesized that cognition is affected by …