Peroxidation of membrane phospholipids (PLs) is a hallmark of ferroptosis. ER and
mitochondria have been implicated in ferroptosis, but whether intracellular PL-peroxidation …

Peroxidation of membrane phospholipids (PLs) is a hallmark of ferroptosis. ER and
mitochondria have been implicated in ferroptosis, but whether intracellular PL-peroxidation …

Ferroptosis is a regulated form of cell death that is driven by a lethal accumulation of lipid
peroxides in cell membranes (Dixon et al., 2012). Recent studies have revealed the …

Cell death is involved in diseases such as cancer and neurodegeneration, and also has a
natural role in the development of multicellular organisms. Although apoptosis has been …

Significance: Ferroptosis is featured by the accumulation of polyunsaturated-lipid
peroxidation on cellular membranes in an iron-dependent manner. Ferroptosis has been …

The inhibition of antioxidant systems of glutathione peroxidase 4 (GPX4) or ferroptosis
suppressor protein 1 (FSP1) causes iron-dependent peroxidation of polyunsaturated …

Ferroptosis is a form of regulated necrosis characterized by the iron-dependent
accumulation of lipid peroxides in cell membranes. However, how lipid oxidation affects …

Ferroptosis is a form of regulated necrosis characterized by the iron-dependent
accumulation of lipid peroxides in cell membranes. However, how lipid oxidation affects …

Enigmatic lipid peroxidation products have been claimed as the proximate executioners of
ferroptosis—a specialized death program triggered by insufficiency of glutathione …

Membrane lipids play important roles in the regulation of cell fate, including the execution of
ferroptosis. Ferroptosis is a non‐apoptotic cell death mechanism defined by iron‐dependent …