Evaluation of a Novel 18F-Labeled Positron-Emission Tomography Perfusion Tracer for the Assessment of Myocardial Infarct Size in Rats
HM Sherif, A Saraste, E Weidl, AW Weber… - Circulation …, 2009 - Am Heart Assoc
Background—The goal of this study was to evaluate a new 18F-labeled positron-emission
tomography (PET) perfusion tracer, 18F BMS747158-02, for the assessment of myocardial …
tomography (PET) perfusion tracer, 18F BMS747158-02, for the assessment of myocardial …
Noninvasive measurement of myocardial activity concentrations and perfusion defect sizes in rats with a new small-animal positron emission tomograph
T Kudo, K Fukuchi, AJ Annala, AF Chatziioannou… - Circulation, 2002 - Am Heart Assoc
Background—We explored the feasibility of measuring regional tracer activity concentrations
and flow defects in myocardium of rats with a high spatial resolution small-animal PET …
and flow defects in myocardium of rats with a high spatial resolution small-animal PET …
Reproducibility and accuracy of non-invasive measurement of infarct size in mice with high-resolution PET/CT
A Greco, MP Petretta, M Larobina, S Gargiulo… - Journal of Nuclear …, 2012 - Springer
Background This study assessed the reproducibility and accuracy of 2-deoxy-2 [18 F] fluoro-
d-glucose (18 F-FDG) for non-invasive quantification of myocardial infarct size in mice by a …
d-glucose (18 F-FDG) for non-invasive quantification of myocardial infarct size in mice by a …
Rubidium-82 PET imaging is feasible in a rat myocardial infarction model
Background Small-animal myocardial infarct models are frequently used in the assessment
of new cardioprotective strategies. A validated quantification of perfusion using a non …
of new cardioprotective strategies. A validated quantification of perfusion using a non …
A new 18F-labeled myocardial PET tracer: myocardial uptake after permanent and transient coronary occlusion in rats
T Higuchi, SG Nekolla, MM Huisman… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Conventional myocardial perfusion PET tracers require onsite tracer production because of
their short radioactive half-lives. To investigate the potential of a new 18F-labeled …
their short radioactive half-lives. To investigate the potential of a new 18F-labeled …
Initial characterization of an 18F-labeled myocardial perfusion tracer
MC Huisman, T Higuchi, S Reder… - Journal of Nuclear …, 2008 - Soc Nuclear Med
PET allows for quantitative, regional myocardial perfusion imaging. The short half-lives of
the perfusion tracers currently in use limit their clinical applicability. Here, the biodistribution …
the perfusion tracers currently in use limit their clinical applicability. Here, the biodistribution …
Accurate noninvasive measurement of infarct size in mice with high-resolution PET
L Stegger, AN Hoffmeier, KP Schäfers… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Reliable, repeatable, and time-efficient noninvasive measurement of infarct size in mice with
PET would benefit studies aimed at the exploration of biochemical and functional changes …
PET would benefit studies aimed at the exploration of biochemical and functional changes …
Cardiac imaging and safety evaluation of BMS747158, a novel PET myocardial perfusion imaging agent, in chronic myocardial compromised rabbits
M Yu, J Bozek, M Guaraldi, M Kagan, M Azure… - Journal of nuclear …, 2010 - Elsevier
Background BMS747158 labeled with 18 F is being developed for PET myocardial perfusion
imaging. Imaging studies showed clear detection of necrotic tissue in acute myocardial …
imaging. Imaging studies showed clear detection of necrotic tissue in acute myocardial …
Characterization of normal and infarcted rat myocardium using a combination of small-animal PET and clinical MRI
T Higuchi, SG Nekolla, A Jankaukas… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The combination of small-animal PET and MRI data provides quantitative in vivo insights
into cardiac pathophysiology, integrating information on biology and morphology. We sought …
into cardiac pathophysiology, integrating information on biology and morphology. We sought …
Evaluation of the Novel Myocardial Perfusion Positron-Emission Tomography Tracer 18F-BMS-747158-02: Comparison to 13N-Ammonia and Validation With …
SG Nekolla, S Reder, A Saraste, T Higuchi, G Dzewas… - Circulation, 2009 - Am Heart Assoc
Background—Positron-emission tomography (PET) tracers for myocardial perfusion are
commonly labeled with short-lived isotopes that limit their widespread clinical use. 18F-BMS …
commonly labeled with short-lived isotopes that limit their widespread clinical use. 18F-BMS …
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- positron emission tomography perfusion
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- positron emission validation with microspheres
- myocardial perfusion validation with microspheres
- infarct size reproducibility and accuracy
- positron emission myocardial perfusion