Comment on:“Drugs That Can Kill a Toddler with One Tablet or Teaspoonful: A 2018 Updated List”

ME Mullins, SJ Fishburn - Clinical drug investigation, 2019 - Springer
In attempting to identify drugs that they believe to be hazardous to small children, Koren and
Nachmani rely heavily on subjective and theoretical considerations. The updated list of 'one …

Clinical effects of exposure to DPP-4 inhibitors as reported to the National Poison Data System

JL Russell, MJ Casavant, HA Spiller… - Journal of medical …, 2014 - Springer
Abstract DPP-4 inhibitors (sitagliptin, saxagliptin, and linagliptin) are approved for the
treatment of diabetes. They are considered safe due to their hyperglycemia dependent …

Drugs that can kill a toddler with one tablet or teaspoonful: a 2018 updated list

G Koren, A Nachmani - Clinical Drug Investigation, 2019 - Springer
Abstract Background and Objective Young children may be accidentally exposed to adult
dose forms of medications, some of which can be fatal, even with a single dose. As …

A retrospective review of isolated gliptin-exposure cases reported to a state poison control system

MA Darracq, JM Toy, T Chen, C Mo… - Clinical Toxicology, 2014 - Taylor & Francis
Abstract Background. The dipeptidyl peptidase-4 (DPP-4) inhibitors sitagliptin, saxagliptin,
and linagliptin are approved by the US Food and Drug Administration in the treatment of …

[HTML][HTML] Diversified pediatric pharmacoepidemiology: an international priority

SM MacLeod - Pediatric Drugs, 2018 - Springer
The article by Tomlin et al.[1] in this issue highlights an area that should be of critical
concern for caregivers committed to optimizing pediatric drug therapy. Significant quality …

Pediatric poisonings: the risk of over-the-counter pharmaceuticals

EQ Hines - Pediatric annals, 2017 - journals.healio.com
Every week in the United States, 56% of children younger than age 18 years and 82% of
adults take at least one medication. Nonprescription medications, including acetaminophen …

[引用][C] Protecting young children from life-threatening drug toxicity

G Koren - The Journal of pediatrics, 2013 - jpeds.com
There is nothing more devastating than losing the life of a young child because of toxicity
caused by the very drug that was supposed to cure or relieve his/her symptoms. Yet, every …

4 Unrelenting Insulin Release: Sulfonylurea/Meglitinide Overdose

M Sheneman, BP Murray, JE Carpenter - books.google.com
Background Sulfonylureas are the oldest class of oral antidiabetic medications and one of
the classes that can lead to hypoglycemia. In fact, the most common adverse effect of these …

The persistent challenge of understanding preventable adverse drug events

L Schroeder, DC Stockwell - Pediatrics, 2018 - publications.aap.org
Adverse drug events (ADEs) are a significant safety risk for hospitalized patients. ‍ 1 Medical
centers devote considerable resources to quality and safety initiatives aimed at mitigating …

[HTML][HTML] Assessing drug safety in children—the role of real-world data

AW McMahon, G Dal Pan - The New England journal of medicine, 2018 - ncbi.nlm.nih.gov
Over the past 20 years, several legislative initiatives in the United States have resulted in
hundreds of clinical trials assessing the treatment effects of various drugs in children. 1 …