Nanoparticle-mediated gene delivery

S Jin, JC Leach, K Ye - Micro and nano technologies in bioanalysis …, 2009 - Springer
Nonviral gene delivery has been gaining considerable attention recently. Although the
efficacy of DNA transfection, which is a major concern, is low in nonviral vector-mediated …

Nanoparticles as nonviral gene delivery vectors

A Ragusa, I García, S Penadés - IEEE transactions on …, 2007 - ieeexplore.ieee.org
Gene therapy, as therapeutic treatment to genetic or acquired diseases, is attracting much
interest in the research community, leading to noteworthy developments over the past two …

Medicated nanoparticle for gene delivery

SL Prabu, TNK Suriyaprakash… - Advanced Technology …, 2017 - books.google.com
Delivering the drug to the target site with a desired concentration to provide therapeutic
effect is a major problem in the drug delivery system. Effectiveness, poor distribution and …

Superparamagnetic nanoparticle delivery of DNA vaccine

FN Al-Deen, C Selomulya, C Ma, RL Coppel - DNA Vaccines: Methods …, 2014 - Springer
The efficiency of delivery of DNA vaccines is often relatively low compared to protein
vaccines. The use of superparamagnetic iron oxide nanoparticles (SPIONs) to deliver genes …

Controlled gene delivery systems: Nanomaterials and chemical approaches

S Ahmadi, N Rabiee, Y Fatahi… - Journal of …, 2020 - ingentaconnect.com
Successful gene therapy depends on the design of effective gene delivery systems. A gene
delivery system is considered a powerful tool for the release of genetic material within cells …

[HTML][HTML] Nanomaterials as transmitters of non-viral gene vectors: A review

AK Alkhawaldeh, AM Rheima, MM Kadhim… - Case Studies in …, 2023 - Elsevier
With the rapid development of nanotechnology in the recent decade, novel DNA and RNA
delivery systems for gene therapy have become available that can be used instead of viral …

[HTML][HTML] Advances in gene delivery systems

S Nimesh, S Halappanavar, NK Kaushik… - BioMed Research …, 2015 - ncbi.nlm.nih.gov
Gene therapy can be defined as incorporation of genetic material, that is, DNA or RNA, in
the cellular gene regulation system, either to correct the expression of a malfunctioning gene …

[HTML][HTML] Recent advances in nanomaterials for gene delivery—a review

MK Riley, W Vermerris - Nanomaterials, 2017 - mdpi.com
With the rapid development of nanotechnology in the recent decade, novel DNA and RNA
delivery systems for gene therapy have become available that can be used instead of viral …

[HTML][HTML] Nanodelivery of nucleic acids

BB Mendes, J Conniot, A Avital, D Yao… - Nature reviews …, 2022 - nature.com
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …

[HTML][HTML] Nanotechnology-based strategies to overcome current barriers in gene delivery

S Mirón-Barroso, EB Domènech… - International journal of …, 2021 - mdpi.com
Nanomaterials are currently being developed for the specific cell/tissue/organ delivery of
genetic material. Nanomaterials are considered as non-viral vectors for gene therapy use …