A newly developed and validated environmentally friendly RP-HPLC stability indicating method for the COVID-19 antiviral Molnupiravir: Application to degradation …
HA Wagdy - Microchemical Journal, 2024 - Elsevier
The SARS-CoV-2 coronavirus pandemic also referred to as COVID-19 is a severe
respiratory illness. Molnupiravir (Moln) is a frequently prescribed antiviral medication used in …
respiratory illness. Molnupiravir (Moln) is a frequently prescribed antiviral medication used in …
LC and LC-HRMS studies on stability behavior of molnupiravir an anti-COVID 19 drug
Molnupiravir is a recently approved drug against the ongoing worldwide pandemic of COVID-
19. The current study endeavors to identify and characterize the degradation products of …
19. The current study endeavors to identify and characterize the degradation products of …
A sustainable approach for the degradation kinetics study and stability assay of the SARS-CoV-2 oral antiviral drug Molnupiravir
Molnupiravir (MPV) is the first direct-acting oral antiviral drug that effectively decreases
nasopharyngeal infections with SARS-CoV-2 virus. The stability of MPV was tested by …
nasopharyngeal infections with SARS-CoV-2 virus. The stability of MPV was tested by …
Innovative eco-friendly stability-indicating HPLC-PDA method for simultaneous determination of the emerging antiviral drugs against COVID-19 infection molnupiravir …
HM Marzouk, AS Gouda, MR Rezk… - Microchemical …, 2024 - Elsevier
The adoption of the principles of green chemistry in analytical procedures lowers the
negative influence on both people and the environment, which presently has become the …
negative influence on both people and the environment, which presently has become the …
White targeted chromatographic screening method of Molnupiravir and its metabolite with degradation kinetics characterization and in-silico toxicity
SARS-CoV-2 virus triggered a worldwide crisis, with world nations putting up massive efforts
to halt its spread. Molnupiravir (MLN) was the first oral, direct-acting antiviral drug approved …
to halt its spread. Molnupiravir (MLN) was the first oral, direct-acting antiviral drug approved …
Green adherent degradation kinetics study of Nirmatrelvir, an oral anti-COVID-19: characterization of degradation products using LC–MS with insilico toxicity profile
The SARS-CoV-2 virus sets up a global catastrophe, and countries all around the world
made significant efforts to halt the spread. Nirmatrelvir (NMV) was lately approved by the …
made significant efforts to halt the spread. Nirmatrelvir (NMV) was lately approved by the …
Eco-friendly based UV spectrophotometric method and analytical quality by design aided stability indicating RP-HPLC technique for the estimation of molnupiravir
D Perumal, M Krishnan, KS Lakshmi - Analytical Chemistry Letters, 2023 - Taylor & Francis
Molnupiravir a novel oral broad-spectrum antiviral drug initially developed for the treatment
of COVID-19, was quantified using UV spectrophotometric and high-performance liquid …
of COVID-19, was quantified using UV spectrophotometric and high-performance liquid …
A validated LC-MS/MS method for determination of antiviral prodrug molnupiravir in human plasma and its application for a pharmacokinetic modeling study in healthy …
A fully validated, simple, rapid and reproducible liquid chromatography-tandem mass
spectrometry method was developed to determine NHC (N-hydroxycytidine), the active …
spectrometry method was developed to determine NHC (N-hydroxycytidine), the active …
A novel stability-indicating HPLC-DAD method for determination of favipiravir, a potential antiviral drug for COVID-19 treatment; application to degradation kinetic …
HM Marzouk, MR Rezk, AS Gouda… - Microchemical …, 2022 - Elsevier
Modern pharmaceutical analysis is paying a lot of attention to the stability of novel drug
formulations as well as establishment of suitable stability-indicating approaches. In the …
formulations as well as establishment of suitable stability-indicating approaches. In the …
A validated LC-MS/MS method for determination of Molnupiravir and Favipiravir in human plasma; Assessment of the remarkable potential synergistic effect against …
HM Marzouk, AS Gouda, MR Rezk… - Microchemical …, 2024 - Elsevier
Several clinical trials were carried out to find the route for an efficient therapy against SARS-
CoV-2 infection. Mono-and dual therapy of various antivirals were investigated and found to …
CoV-2 infection. Mono-and dual therapy of various antivirals were investigated and found to …