The glycogen synthase kinase 3 (GSK3) inhibitor, 6-bromoindirubin-3′-oxime (BIO), is a
key regulator of many signaling pathways to maintain pluripotency of human and mouse …

In the present study, we used a serum-free culture media to propagate goat putative
spermatogonial stem cells (SSCs) and evaluated the effect of crucial growth factors on …

Introduction Presently the techniques for making transgenic animals are cumbersome,
required costly instruments and trained man-power. The ability of spermatogonial stem cells …

6-Bromoindirubin-3′-oxime (BIO), which is one of the glycogen synthase kinase 3 inhibitors
and a key regulator of numerous signaling pathways, was reported to be capable of …

Male germline stem cells (mGSC) reside in the basement of seminiferous tubules of the
testis and have the capacity of self-renewal and differentiation into sperm throughout the life …

Male germline stem cells (mGSCs) are unique adult germ cells with self-renewal potential
and spermatogenesis function in the testis. However, further studies are needed to establish …

Purpose Gonocytes are primitive male germ cells residing in the neonatal testes and are
unipotent in nature, but also have pluripotent stem cell ability in mice under appropriate …

In this study, we attempted to establish a culture system for in vitro spermatogenesis from
spermatogonial stem cells (SSCs) of Bama mini-pig. Dissociated testicular cells from 1 …

Objective It is widely believed that in most female mammalian neonates, all germ cells enter
meiosis to form the primary oocyte at the end of foetal development, and as a result, the …

Male germline stem cells (mGSCs), in charge for the fertility in male testis, are the only kind
of adult stem cells that transmit genetic information to next generation, with promising …