Bayesian random segmentation models to identify shared copy number aberrations for array CGH data

V Baladandayuthapani, Y Ji, R Talluri… - Journal of the …, 2010 - Taylor & Francis
Array-based comparative genomic hybridization (aCGH) is a high-resolution, high-
throughput technique for studying the genetic basis of cancer. The resulting data consist of …

A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations

DA Engler, G Mohapatra, DN Louis, RA Betensky - Biostatistics, 2006 - academic.oup.com
DNA sequence copy number has been shown to be associated with cancer development
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …

Stochastic segmentation models for array-based comparative genomic hybridization data analysis

TL Lai, H Xing, N Zhang - Biostatistics, 2008 - academic.oup.com
Array-based comparative genomic hybridization (array-CGH) is a high throughput, high
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …

Analysis of array CGH data for cancer studies using fused quantile regression

Y Li, J Zhu - Bioinformatics, 2007 - academic.oup.com
Motivation: The identification of DNA copy number changes provides insights that may
advance our understanding of initiation and progression of cancer. Array-based comparative …

Bayesian hidden Markov modeling of array CGH data

S Guha, Y Li, D Neuberg - Journal of the American Statistical …, 2008 - Taylor & Francis
Genomic alterations have been linked to the development and progression of cancer. The
technique of comparative genomic hybridization (CGH) yields data consisting of …

A comparison study: applying segmentation to array CGH data for downstream analyses

H Willenbrock, J Fridlyand - Bioinformatics, 2005 - academic.oup.com
Motivation: Array comparative genomic hybridization (CGH) allows detection and mapping
of copy number of DNA segments. A challenge is to make inferences about the copy number …

Computational methods for identification of recurrent copy number alteration patterns by array CGH

SP Shah - Cytogenetic and genome research, 2009 - karger.com
Recurrent DNA copy number alterations (CNA) are widely studied in diagnostic and
cytogenetic cancer research. CNAs reveal locations that may alter gene dosage and thus …

Integrating copy number polymorphisms into array CGH analysis using a robust HMM

SP Shah, X Xuan, RJ DeLeeuw, M Khojasteh… - …, 2006 - academic.oup.com
Motivation: Array comparative genomic hybridization (aCGH) is a pervasive technique used
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …

[HTML][HTML] Estimation of tumor heterogeneity using CGH array data

K Wang, J Li, S Li, L Bolund, C Wiuf - BMC bioinformatics, 2009 - Springer
Background Array-based comparative genomic hybridization (CGH) is a commonly-used
approach to detect DNA copy number variation in whole genome-wide screens. Several …

Normalized, segmented or called aCGH data?

WN Van Wieringen, MA Van De Wiel… - Cancer …, 2007 - journals.sagepub.com
Array comparative genomic hybridization (aCGH) is a high-throughput lab technique to
measure genome-wide chromosomal copy numbers. Data from aCGH experiments require …