Bayesian random segmentation models to identify shared copy number aberrations for array CGH data
Array-based comparative genomic hybridization (aCGH) is a high-resolution, high-
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations
DA Engler, G Mohapatra, DN Louis, RA Betensky - Biostatistics, 2006 - academic.oup.com
DNA sequence copy number has been shown to be associated with cancer development
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …
Stochastic segmentation models for array-based comparative genomic hybridization data analysis
Array-based comparative genomic hybridization (array-CGH) is a high throughput, high
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …
Analysis of array CGH data for cancer studies using fused quantile regression
Y Li, J Zhu - Bioinformatics, 2007 - academic.oup.com
Motivation: The identification of DNA copy number changes provides insights that may
advance our understanding of initiation and progression of cancer. Array-based comparative …
advance our understanding of initiation and progression of cancer. Array-based comparative …
Bayesian hidden Markov modeling of array CGH data
Genomic alterations have been linked to the development and progression of cancer. The
technique of comparative genomic hybridization (CGH) yields data consisting of …
technique of comparative genomic hybridization (CGH) yields data consisting of …
A comparison study: applying segmentation to array CGH data for downstream analyses
H Willenbrock, J Fridlyand - Bioinformatics, 2005 - academic.oup.com
Motivation: Array comparative genomic hybridization (CGH) allows detection and mapping
of copy number of DNA segments. A challenge is to make inferences about the copy number …
of copy number of DNA segments. A challenge is to make inferences about the copy number …
Computational methods for identification of recurrent copy number alteration patterns by array CGH
SP Shah - Cytogenetic and genome research, 2009 - karger.com
Recurrent DNA copy number alterations (CNA) are widely studied in diagnostic and
cytogenetic cancer research. CNAs reveal locations that may alter gene dosage and thus …
cytogenetic cancer research. CNAs reveal locations that may alter gene dosage and thus …
Integrating copy number polymorphisms into array CGH analysis using a robust HMM
SP Shah, X Xuan, RJ DeLeeuw, M Khojasteh… - …, 2006 - academic.oup.com
Motivation: Array comparative genomic hybridization (aCGH) is a pervasive technique used
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
[HTML][HTML] Estimation of tumor heterogeneity using CGH array data
K Wang, J Li, S Li, L Bolund, C Wiuf - BMC bioinformatics, 2009 - Springer
Background Array-based comparative genomic hybridization (CGH) is a commonly-used
approach to detect DNA copy number variation in whole genome-wide screens. Several …
approach to detect DNA copy number variation in whole genome-wide screens. Several …
Normalized, segmented or called aCGH data?
WN Van Wieringen, MA Van De Wiel… - Cancer …, 2007 - journals.sagepub.com
Array comparative genomic hybridization (aCGH) is a high-throughput lab technique to
measure genome-wide chromosomal copy numbers. Data from aCGH experiments require …
measure genome-wide chromosomal copy numbers. Data from aCGH experiments require …