Inhibition of pancreatic lipase (PL) is considered one of the important therapeutic
interventions against obesity. In the present study, the inhibition of porcine (mammalian) PL …

The targeted compounds which are Schiff base derivatives were prepared by reaction of 6-
(4-phenyl-piperazin-1-yl) pyridine-3-ylamine with 2-hydroxy and 2, 6-dichloro …

Obesity is the worst health risk worldwide, which is linked to a number of diseases.
Pancreatic lipase is considered as an affective cause of obesity and can be a major target …

Pancreatic lipase (PL) is the main digestive enzyme that is responsible for breaking
triglycerides into smaller components for absorption. Inhibition of PL can effectively reduce …

Pancreatic lipase (PL) is a keen target for anti-obesity therapy that reduces dietary fat
absorption. Here, we investigated the binding patterns of 220 PL inhibitors having …

A series of coumarin-3-carboxamide analogues has been designed, synthesized and
assessed for their ability to inhibit pancreatic lipase (PL). Amongst all the synthesized …

Obesity, characterized by excessive fat accumulation, is a major health concern. Inhibition of
human pancreatic lipase, an enzyme involved in fat digestion, offers a potential strategy for …

Inhibition of pancreatic lipase (PL) is used to treat dyslipidemias and obesity. Phenolic
compounds are highly bioactive molecules that can inhibit various enzymes. Our aim was to …

According to the world health organization (WHO), recent worldwide reported health cases
of obesity have nearly tripled those of 1975 with over 650 million obese populations [1] …

Obesity is becoming a top global health problem. Inhibition of digestive enzymes is an
effective approach in weight management due to the reduction of energy absorption. In this …