Pipolins are bimodular platforms that maintain a reservoir of defense systems exchangeable with various bacterial genetic mobile elements
V Mateo Caceres, M Redrejo Rodriguez - bioRxiv, 2024 - biorxiv.org
Defense genes gather in diverse types of genomic islands in bacteria and provide immunity
against viruses and other genetic mobile elements. Here, we disclose pipolins, previously …
against viruses and other genetic mobile elements. Here, we disclose pipolins, previously …
ExplorePipolin: reconstruction and annotation of bacterial mobile elements from draft genomes
L Chuprikova, V Mateo-Cáceres, M de Toro… - bioRxiv, 2022 - biorxiv.org
Motivation Detailed and accurate analysis of mobile genetic elements (MGEs) in bacteria is
essential to deal with the current threat of multiresistant microbes. The overwhelming use of …
essential to deal with the current threat of multiresistant microbes. The overwhelming use of …
ExplorePipolin: reconstruction and annotation of piPolB-encoding bacterial mobile elements from draft genomes
L Chuprikova, V Mateo-Cáceres… - Bioinformatics …, 2022 - academic.oup.com
Motivation Detailed and accurate analysis of mobile genetic elements (MGEs) in bacteria is
essential to deal with the current threat of multiresistant microbes. The overwhelming use of …
essential to deal with the current threat of multiresistant microbes. The overwhelming use of …
[HTML][HTML] High diversity and variability of pipolins among a wide range of pathogenic Escherichia coli strains
SC Flament-Simon, M de Toro, L Chuprikova… - Scientific Reports, 2020 - nature.com
Self-synthesizing transposons are integrative mobile genetic elements (MGEs) that encode
their own B-family DNA polymerase (PolB). Discovered a few years ago, they are proposed …
their own B-family DNA polymerase (PolB). Discovered a few years ago, they are proposed …
[PDF][PDF] 2 High diversity and variability of pipolins among a wide range of 3 pathogenic Escherichia coli strains
JMG Blanco, M Salas, J Blanco, M Redrejo-Rodríguez - academia.edu
63 Mobile genetic elements (MGE), comprising bacteriophages, transposons, plasmids, 64
and insertion sequences, contribute to the great plasticity of the bacterial genome, 65 …
and insertion sequences, contribute to the great plasticity of the bacterial genome, 65 …
Mobile Integrons Encode Phage Defence Systems
N Kieffer, A Hipolito, P Blanco, T Delobelle, FM Ojeda… - bioRxiv, 2024 - biorxiv.org
Integrons are bacterial genetic elements that capture, stockpile and modulate the expression
of genes encoded in integron cassettes. Mobile Integrons (MI) are borne on plasmids, acting …
of genes encoded in integron cassettes. Mobile Integrons (MI) are borne on plasmids, acting …
[HTML][HTML] Microbial genomics: the expanding universe of bacterial defense systems
KJ Forsberg, HS Malik - Current Biology, 2018 - cell.com
Bacteria protect themselves against infection using multiple defensive systems that move by
horizontal gene transfer and accumulate in genomic 'defense islands'. A recent study …
horizontal gene transfer and accumulate in genomic 'defense islands'. A recent study …
[HTML][HTML] Functional enrichment of integrons: Facilitators of antimicrobial resistance and niche adaptation
Integrons are genetic elements, found among diverse bacteria and archaea, that capture
and rearrange gene cassettes to rapidly generate genetic diversity and drive adaptation …
and rearrange gene cassettes to rapidly generate genetic diversity and drive adaptation …
Going viral: The role of mobile genetic elements in bacterial immunity
Bacteriophages and other mobile genetic elements (MGEs) pose a significant threat to
bacteria, subjecting them to constant attacks. In response, bacteria have evolved a …
bacteria, subjecting them to constant attacks. In response, bacteria have evolved a …
ExplorePipolin: a pipeline for identification and exploration of pipolins, novel mobile genetic elements widespread among bacteria
L Chuprikova - 2020 - repositorio.uam.es
Pipolins constitute a new group of self-synthesizing or self-replicating mobile genetic
elements (MGEs), encoding for their own replicative DNA polymerase B. These elements …
elements (MGEs), encoding for their own replicative DNA polymerase B. These elements …