[HTML][HTML] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells

NW Gouwens, SA Sorensen, F Baftizadeh, A Budzillo… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

BR Lee, R Dalley, JA Miller, T Chartrand, J Close… - Science, 2023 - science.org
Human cortex transcriptomic studies have revealed a hierarchical organization of γ-
aminobutyric acid–producing (GABAergic) neurons from subclasses to a high diversity of …

Classification of electrophysiological and morphological neuron types in the mouse visual cortex

NW Gouwens, SA Sorensen, J Berg, C Lee… - Nature …, 2019 - nature.com
Understanding the diversity of cell types in the brain has been an enduring challenge and
requires detailed characterization of individual neurons in multiple dimensions. To …

[HTML][HTML] Transcriptional architecture of synaptic communication delineates GABAergic neuron identity

A Paul, M Crow, R Raudales, M He, J Gillis, ZJ Huang - Cell, 2017 - cell.com
Understanding the organizational logic of neural circuits requires deciphering the biological
basis of neuronal diversity and identity, but there is no consensus on how neuron types …

The diversity of GABAergic neurons and neural communication elements

ZJ Huang, A Paul - Nature Reviews Neuroscience, 2019 - nature.com
The phenotypic diversity of cortical GABAergic neurons is probably necessary for their
functional versatility in shaping the spatiotemporal dynamics of neural circuit operations …

[HTML][HTML] Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex

AM Kerlin, ML Andermann, VK Berezovskii, RC Reid - Neuron, 2010 - cell.com
Different subtypes of GABAergic neurons in sensory cortex exhibit diverse morphology,
histochemical markers, and patterns of connectivity. These subtypes likely play distinct roles …

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

B Tasic, V Menon, TN Nguyen, TK Kim, T Jarsky… - Nature …, 2016 - nature.com
Nervous systems are composed of various cell types, but the extent of cell type diversity is
poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual …

[HTML][HTML] Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics

KD Harris, H Hochgerner, NG Skene, L Magno… - PLoS …, 2018 - journals.plos.org
Understanding any brain circuit will require a categorization of its constituent neurons. In
hippocampal area CA1, at least 23 classes of GABAergic neuron have been proposed to …

[HTML][HTML] Evolution of neuronal types and families

D Arendt, PY Bertucci, K Achim, JM Musser - Current opinion in …, 2019 - Elsevier
Highlights•Solving nervous system evolution requires cross-species comparison of neuronal
types.•Neuronal types are commonly defined by their specific structure and function.•We …

Neuronal cell-type classification: challenges, opportunities and the path forward

H Zeng, JR Sanes - Nature Reviews Neuroscience, 2017 - nature.com
Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …