The mechanism (s) of action of antioxidants: From scavenging reactive oxygen/nitrogen species to redox signaling and the generation of bioactive secondary …

A Hunyadi - Medicinal research reviews, 2019 - Wiley Online Library
Small molecule, dietary antioxidants exert a remarkably broad range of bioactivities, and
many of these can be explained by the influence of antioxidants on the redox homeostasis …

Understanding mechanisms of antioxidant action in health and disease

B Halliwell - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Antioxidants: positive or negative actors?

B Salehi, M Martorell, JL Arbiser, A Sureda, N Martins… - Biomolecules, 2018 - mdpi.com
The term “antioxidant” is one of the most confusing definitions in biological/medical
sciences. In chemistry,“antioxidant” is simply conceived “a compound that removes reactive …

Oxidative stress mitigation by antioxidants-an overview on their chemistry and influences on health status

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2021 - Elsevier
The present review paper focuses on the chemistry of oxidative stress mitigation by
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …

Free radicals and antioxidants–quo vadis?

B Halliwell - Trends in pharmacological sciences, 2011 - cell.com
The field of free radicals and antioxidants, or 'redox biology', is fundamental to aerobic life.
Aerobes constantly make reactive species, but modulate their actions by synthesizing …

Antioxidants and prevention of chronic disease

JK Willcox, SL Ash, GL Catignani - Critical reviews in food science …, 2004 - Taylor & Francis
The generation of reactive oxygen species (ROS) and other free radicals (R•) during
metabolism is a necessary and normal process that ideally is compensated for by an …

Free radicals, natural antioxidants, and their reaction mechanisms

SB Nimse, D Pal - RSC advances, 2015 - pubs.rsc.org
The normal biochemical reactions in our body, increased exposure to the environment, and
higher levels of dietary xenobiotic's result in the generation of reactive oxygen species …

Antioxidants in translational medicine

HHHW Schmidt, R Stocker, C Vollbracht… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: It is generally accepted that reactive oxygen species (ROS) scavenging
molecules or antioxidants exert health-promoting effects and thus their consumption as food …

[HTML][HTML] Natural antioxidants: function and sources

Y Shebis, D Iluz, Y Kinel-Tahan, Z Dubinsky… - 2013 - scirp.org
The definition of antioxidants, given in 1995 by Halliwell and Gutteridge, stated that an
antioxidant is “any substance that, when present at low concentrations compared with that of …

[HTML][HTML] Applications of antioxidants in metabolic disorders and degenerative diseases: Mechanistic approach

MM Abdel-Daim, OS El-Tawil, SG Bungau… - … medicine and cellular …, 2019 - ncbi.nlm.nih.gov
Oxidative stress (resulting from redox homeostasis imbalance between prooxidative and
antioxidant systems) is a major player in the pathogenesis of many inflammatory, metabolic …