A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated enhancer clusters

W Wang, S Qiao, G Li, J Cheng, C Yang… - Nucleic acids …, 2022 - academic.oup.com
As an oncogenic transcription factor, Yin Yang 1 (YY1) regulates enhancer and promoter
connection. However, gaps still exist in understanding how YY1 coordinates coactivators …

Yin Yang 1: a multifaceted protein beyond a transcription factor

Z Deng, P Cao, MM Wan, G Sui - Transcription, 2010 - Taylor & Francis
As a transcription factor, Yin Yang 1 (YY1) regulates the transcription of a dazzling list of
genes and the number of its targets still mounts. Recent studies revealed that YY1 …

[HTML][HTML] The why of YY1: mechanisms of transcriptional regulation by Yin Yang 1

TCJ Verheul, L van Hijfte, E Perenthaler… - Frontiers in cell and …, 2020 - frontiersin.org
First described in 1991, Yin Yang 1 (YY1) is a transcription factor that is ubiquitously
expressed throughout mammalian cells. It regulates both transcriptional activation and …

YY1 functions with INO80 to activate transcription

Y Cai, J Jin, T Yao, AJ Gottschalk… - Nature structural & …, 2007 - nature.com
Ubiquitously expressed transcription factor Yin-Yang-1 (YY1) controls expression of many
genes. YY1 is tightly associated with the human ATP-dependent INO80-like chromatin …

Yin Yang 1 extends the Myc-related transcription factors network in embryonic stem cells

P Vella, I Barozzi, A Cuomo, T Bonaldi… - Nucleic acids …, 2012 - academic.oup.com
Abstract The Yin Yang 1 (YY1) transcription factor is a master regulator of development,
essential for early embryogenesis and adult tissues formation. YY1 is the mammalian …

The Yin and Yang of YY 1 in tumor growth and suppression

LM Khachigian - International journal of cancer, 2018 - Wiley Online Library
Yin Yang‐1 (YY1) is a zinc finger protein and member of the GLI‐Kruppel family that can
activate or inactivate gene expression depending on interacting partners, promoter context …

Transcription factor YY1: structure, function, and therapeutic implications in cancer biology

S Gordon, G Akopyan, H Garban, B Bonavida - Oncogene, 2006 - nature.com
The ubiquitous transcription factor Yin Yang 1 (YY1) is known to have a fundamental role in
normal biologic processes such as embryogenesis, differentiation, replication, and cellular …

Yin yang 1 expression in human tumors

A Zaravinos, DA Spandidos - Cell cycle, 2010 - Taylor & Francis
The Yin Yang 1 (YY1) transcription factor has been identified to target a plethora of potential
target genes, the products of which are important for proliferation and differentiation. The …

Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects

ML Atchison, A Basu, K Zaprazna… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
ABSTRACT Yin Yang 1 (YY1) is a ubiquitously expressed transcription factor that performs
numerous functions including transcriptional regulation, cell growth control, apoptosis, large …

Everything you have ever wanted to know about Yin Yang 1......

Y Shi, JS Lee, KM Galvin - Biochimica et Biophysica Acta (BBA)-Reviews …, 1997 - Elsevier
It has been well-documented that transcription factors play pivotal roles in cell growth
control, development and differentiation. Defects in these proteins have been correlated with …