[HTML][HTML] Brain iron homeostasis and mental disorders

Q Wu, Q Ren, J Meng, WJ Gao, YZ Chang - Antioxidants, 2023 - mdpi.com
Iron plays an essential role in various physiological processes. A disruption in iron
homeostasis can lead to severe consequences, including impaired neurodevelopment …

[HTML][HTML] Brain iron metabolism, redox balance and neurological diseases

G Gao, L You, J Zhang, YZ Chang, P Yu - Antioxidants, 2023 - mdpi.com
The incidence of neurological diseases, such as Parkinson's disease, Alzheimer's disease
and stroke, is increasing. An increasing number of studies have correlated these diseases …

[HTML][HTML] Multilevel impacts of iron in the brain: the cross talk between neurophysiological mechanisms, cognition, and social behavior

A Ferreira, P Neves, R Gozzelino - Pharmaceuticals, 2019 - mdpi.com
Iron is a critical element for most organisms, which plays a fundamental role in the great
majority of physiological processes. So much so, that disruption of iron homeostasis has …

[HTML][HTML] Iron imbalance in neurodegeneration

S Levi, M Ripamonti, AS Moro, A Cozzi - Molecular Psychiatry, 2024 - nature.com
Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …

Brain iron metabolism and CNS diseases

A Thirupathi, YZ Chang - Brain Iron Metabolism and CNS Diseases, 2019 - Springer
Iron is the most abundant trace element in the human body. It is well known that iron is an
important component of hemoglobin involved in the transport of oxygen. As a component of …

[HTML][HTML] A delicate balance: Iron metabolism and diseases of the brain

D Hare, S Ayton, A Bush, P Lei - Frontiers in aging neuroscience, 2013 - frontiersin.org
Iron is the most abundant transition metal within the brain, and is vital for a number of
cellular processes including neurotransmitter synthesis, myelination of neurons, and …

Mitochondrial iron metabolism and neurodegenerative diseases

R Cheng, VV Dhorajia, J Kim, Y Kim - Neurotoxicology, 2022 - Elsevier
Iron is a key element for mitochondrial function and homeostasis, which is also crucial for
maintaining the neuronal system, but too much iron promotes oxidative stress. A large body …

[HTML][HTML] Age-related changes and sex-related differences in brain iron metabolism

T Grubić Kezele, B Ćurko-Cofek - Nutrients, 2020 - mdpi.com
Iron is an essential element that participates in numerous cellular processes. Any disruption
of iron homeostasis leads to either iron deficiency or iron overload, which can be detrimental …

[HTML][HTML] The aging of iron man

A Ashraf, M Clark, PW So - Frontiers in aging neuroscience, 2018 - frontiersin.org
Brain iron is tightly regulated by a multitude of proteins to ensure homeostasis. Iron
dyshomeostasis has become a molecular signature associated with aging which is …

Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities

N Singh, S Haldar, AK Tripathi, K Horback… - Antioxidants & redox …, 2014 - liebertpub.com
Iron has emerged as a significant cause of neurotoxicity in several neurodegenerative
conditions, including Alzheimer's disease (AD), Parkinson's disease (PD), sporadic …