Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects

H Khan, H Ullah, SM Nabavi - Food and Chemical Toxicology, 2019 - Elsevier
The liver is the most essential organ of the body performing vital functions. Hepatic disorders
affect the physiological and biochemical functions of the body. These disorders include …

Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress

JH Park, BM Lee, HS Kim - Journal of Toxicology and …, 2021 - Taylor & Francis
Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against
several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties …

Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation …

S Gao, X Duan, X Wang, D Dong, D Liu, X Li… - Food and Chemical …, 2013 - Elsevier
Oxidative stress is one of the major mechanisms implicated in inorganic arsenic poisoning.
Curcumin is a natural phenolic compound with impressive antioxidant properties. What's …

A review of the role of curcumin in metal induced toxicity

E Smirnova, M Moniruzzaman, S Chin, A Sureshbabu… - Antioxidants, 2023 - mdpi.com
Metal toxicity poses a potential global threat to the environment and living beings. Their
numerous agricultural, medical, industrial, domestic, and technological applications result in …

Cadmium‐induced toxicity is rescued by curcumin: a review

M Mohajeri, M Rezaee, A Sahebkar - Biofactors, 2017 - Wiley Online Library
Cadmium (Cd) is one of the most common environmental and occupational heavy metals
with extended distribution. Exposure to Cd may be associated with several deleterious …

Curcumin functions as an anti‐inflammatory and antioxidant agent on arsenic‐induced hepatic and kidney injury by inhibiting MAPKs/NF‐κB and activating Nrf2 …

G Xu, Y Gu, N Yan, Y Li, L Sun, B Li - Environmental toxicology, 2021 - Wiley Online Library
Chronic arsenic exposure has been associated with various toxic effects, especially to the
organs of liver and kidney. As a plant polyphenol, curcumin is the most vital bioactive …

Effects of nanoparticle‐encapsulated curcumin on arsenic‐induced liver toxicity in rats

P Sankar, A Gopal Telang, R Kalaivanan… - Environmental …, 2015 - Wiley Online Library
We investigated the therapeutic effectiveness of the nanoparticle‐encapsulated curcumin
(CUR‐NP) against sodium arsenite‐induced hepatic oxidative damage in rats. The CUR‐NP …

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

EO Farombi, S Shrotriya, HK Na, SH Kim… - Food and Chemical …, 2008 - Elsevier
Curcumin (diferuloymethane), a yellow colouring agent present in the rhizome of Curcuma
longa Linn (Zingiberaceae), has been reported to possess anti-inflammatory, antioxidant …

Hepatoprotective and nephroprotective effect of curcumin against copper toxicity in rats

EA Hashish, SA Elgaml - Indian journal of clinical biochemistry, 2016 - Springer
Curcumin is a natural anti-inflammatory and antioxidant with several potential health
benefits. Although it has been examined in several metals toxicity studies, but its role in the …