Profiling the early molecular response of the human bronchial epithelium to Aspergillus fumigatus using a multi-omics approach

A Toor - 2018 - open.library.ubc.ca
Aspergillus fumigatus (A. fumigatus) is an opportunistic fungal pathogen that is widely
distributed in nature through the release of conidiospores (conidia). Upon inhalation, fungal …

Profiling Early Molecular Responses in Primary Human Bronchial Epithelial Air-Liquid Interface Cultures Exposed to Aspergillus Fumigatus Conidia

A Toor, L Culibrk, GK Singhera, WL Tam… - C60 …, 2018 - atsjournals.org
Rationale Aspergillus fumigatus (A. fumigatus) is an opportunistic fungal pathogen that is
widely distributed in nature through the release of conidia. Upon inhalation, fungal conidia …

[HTML][HTML] Transcriptomic and proteomic host response to Aspergillus fumigatus conidia in an air-liquid interface model of human bronchial epithelium

A Toor, L Culibrk, GK Singhera, KM Moon, A Prudova… - PloS one, 2018 - journals.plos.org
Aspergillus fumigatus (A. fumigatus) is a wide-spread fungus that is a potent allergen in
hypersensitive individuals but also an opportunistic pathogen in immunocompromised …

[HTML][HTML] Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus

P Gomez, TL Hackett, MM Moore, DA Knight… - BMC genomics, 2010 - Springer
Background Aspergillus fumigatus (A. fumigatus) is a ubiquitous fungus which reproduces
asexually by releasing abundant airborne conidia (spores), which are easily respirable. In …

[PDF][PDF] Research article Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus

P Gomez, TL Hackett, MM Moore, DA Knight… - 2010 - bmcgenomics.biomedcentral.com
Background: Aspergillus fumigatus (A. fumigatus) is a ubiquitous fungus which reproduces
asexually by releasing abundant airborne conidia (spores), which are easily respirable. In …

Development of a Dual Organism Model for Aspergillus Fumigatus Spores and Human Airway Epithelial Cells at the Single Cell-Spore Level

WL Tam, A Toor, GK Singhera, B Sahin… - B62. LUNG …, 2018 - atsjournals.org
Rationale Aspergillus fumigatus is a saprotrophic filamentous fungus capable of causing a
number of infectious respiratory diseases in susceptible individuals. The initial stages of …

Probing the interaction of Aspergillus fumigatus conidia and human airway epithelial cells by transcriptional profiling in both species

P Gomez - 2010 - open.library.ubc.ca
The cells of the airway epithelium play critical roles in host defense to inhaled irritants, and
in asthma pathogenesis. These cells are constantly exposed to environmental factors …

[HTML][HTML] Dual Organism Transcriptomics of Airway Epithelial Cells Interacting with Conidia of Aspergillus fumigatus

JL Oosthuizen, P Gomez, J Ruan, TL Hackett… - PLoS …, 2011 - journals.plos.org
Background Given the complex nature of the responses that can occur in host-pathogen
interactions, dual transcriptomics offers a powerful method of elucidating these interactions …

[HTML][HTML] Transcriptome Profiles of Human Lung Epithelial Cells A549 Interacting with Aspergillus fumigatus by RNA-Seq

F Chen, C Zhang, X Jia, S Wang, J Wang, Y Chen… - PloS one, 2015 - journals.plos.org
Lung epithelial cells constitute the first defense line of host against the inhaled Aspergillus
fumigatus; however, the transcriptional response of human alveolar type II epithelial cells …

[图书][B] Analysis of the interactions between Aspergillus fumigatus, Pseudomonas aeruginosa and a model of the alveolar surface

A Margalit - 2019 - search.proquest.com
Aspergillus fumigatus and Pseudomonas aeruginosa are the most prevalent fungal and
bacterial pathogens associated with cystic fibrosis (CF)-related infections, respectively …