The renin–angiotensin–aldosterone system (RAAS) impacts cardiovascular homeostasis via
direct actions on peripheral blood vessels and via modulation of the autonomic nervous …

The renin–angiotensin system (RAS) and the sympathetic nervous system (SNS) are closely
interrelated. Stimulation of the SNS results in an increased renal renin release through …

The sympathetic nervous system plays a critical role in the pathogenesis of hypertension.
The central nervous system (CNS) organizes the sympathetic outflow and various inputs …

Angiotensin II (Ang II), an ancient peptide, evolved to carry out a variety of biological
functions, in order to meet the needs of diverse organisms. The negative feedback nature of …

This review focuses on the dysfunction of the intrinsic brain renin–angiotensin system (RAS)
in the pathogenesis of hypertension. Hyperactivity of the brain RAS plays a critical role in …

Angiotensin II (AngII) is a pivotal peptide implicated in the regulation of blood pressure. In
addition to its systemic vascular and renal effects, AngII acts centrally to modulate the …

The renin-angiotensin system plays an important role in the regulation of arterial blood
pressure and in the development of some forms of clinical and experimental hypertension. It …

There is considerable evidence that the sympathetic nervous system plays an important role
in the pathogenesis of hypertension. 1–3 However, the factors that chronically influence …

Chronic intravenous angiotensin II (Ang II) has been widely used to establish centrally
mediated hypertension in experimental animals, and disruption of Ang II activity is a frontline …

In the brain, angiotensinergic pathways play a major role in chronic regulation of
cardiovascular and electrolyte homeostasis. Increases in plasma angiotensin II (Ang II) …