Ocular drug delivery is a challenging but fascinating topical route of administration. Although
the eye is easily accessible to common drug formulations such as drops, its complex …

Highlights•Electrospinning systems (ES) have huge potential for the development of
promising ocular drug delivery systems.•Ocular applications of currently researched ES …

A serious problem of the treatment of eye diseases is the very short residence time of the
drug. The majority of the drug is cleared within few seconds due to the poor capability of the …

Nanofibers due to their unique properties such as high surface-to-volume ratio, porous
structure, mechanical strength, flexibility and their resemblance to the extracellular matrix …

Electrospun fibers have been gaining popularity in ocular drug delivery and cellular
therapies. However, most of electrospun fibers are planar-shape membrane with large …

Background: Dexamethasone is currently available as a suspension for the treatment of
anterior ocular inflammatory diseases that are given through eye drops. However, less than …

Background: Levofloxacin is available in the form of an eye drop solution for the treatment of
ocular bacterial infection and inflammatory diseases. Below 5% of the drug gets absorbed …

This chapter describes recently designed and developed nanofiber scaffolds used for
ophthalmic tissue engineering applications. In recent decades, ophthalmic diseases have …

Due to the rapid clearance of external agents from the surface of the cornea, conventional
ocular formulations usually require frequent and long duration of administration to achieve a …

Purpose: The poor bioavailability of drugs in the ocular delivery systems is an important
issue and development of delivery systems with prolonged release profile could be in a …