Polymorphisms of rs2483205 and rs562556 in the PCSK9 gene are associated with coronary artery disease and cardiovascular risk factors
MT Gai, D Adi, XC Chen, F Liu, X Xie, YN Yang… - Scientific Reports, 2021 - nature.com
PCSK9 plays a crucial role in lipid metabolism. This case–control study explored the
associations of novel single nucleotide polymorphisms (SNPs) of the PCSK9 gene with …
associations of novel single nucleotide polymorphisms (SNPs) of the PCSK9 gene with …
Serum PCSK9 levels, but not PCSK9 polymorphisms, are associated with CAD risk and lipid profiles in southern Chinese Han population
G Cai, L Yu, Z Huang, L Li, X Fu - Lipids in Health and Disease, 2018 - Springer
Background Genetic and environment factors affect the occurrence and development of
coronary artery disease (CAD). Proprotein convertase subtilisin/kexin type 9 (PCSK9), has …
coronary artery disease (CAD). Proprotein convertase subtilisin/kexin type 9 (PCSK9), has …
What is the impact of PCSK9 rs505151 and rs11591147 polymorphisms on serum lipids level and cardiovascular risk: a meta-analysis
C Qiu, P Zeng, X Li, Z Zhang, B Pan, ZYF Peng… - Lipids in health and …, 2017 - Springer
Background PCSK9 rs505151 and rs11591147 polymorphisms are identified as gain-and
loss-of-function mutations, respectively. The effects of these polymorphisms on serum lipid …
loss-of-function mutations, respectively. The effects of these polymorphisms on serum lipid …
PCSK9 E670G polymorphism increases risk of coronary artery disease in a Chinese Han population
Z Lin, SH Wang, DY Wei, LM Wang… - Journal of …, 2019 - journals.sagepub.com
Objective Coronary artery disease (CAD) is the leading cause of morbidity and mortality in
the world. The proprotein convertase subtilisin/kexin type 9 (PCSK9) E670G polymorphism …
the world. The proprotein convertase subtilisin/kexin type 9 (PCSK9) E670G polymorphism …
PCSK9 Gene E670G Polymorphism and Coronary Artery Disease: An Updated Meta-Analysis of 5,484 Subjects
Y Li, H Wang, X Yang, H Geng, G Gong… - Frontiers in …, 2020 - frontiersin.org
Objective: Research has shown a possible relationship between the E670G polymorphism
of the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and an increased risk of …
of the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and an increased risk of …
The PCSK9 gene E670G polymorphism affects low-density lipoprotein cholesterol levels but is not a risk factor for coronary artery disease in ethnic Chinese in …
LA Hsu, MS Teng, YL Ko, CJ Chang, S Wu… - Clinical chemistry and …, 2009 - degruyter.com
Abstract Background: An E670G polymorphism of the exon 12 of the proprotein convertase
subtilisin/kexin type 9 (PCSK9) gene was recently found to be associated with increased …
subtilisin/kexin type 9 (PCSK9) gene was recently found to be associated with increased …
Association between PCSK9 and LDLR gene polymorphisms with coronary heart disease: case-control study and meta-analysis
L Zhang, F Yuan, P Liu, L Fei, Y Huang, L Xu, L Hao… - Clinical …, 2013 - Elsevier
OBJECTIVE: To explore the association of rs11206510 (PCSK9 gene) and rs1122608
(LDLR gene) polymorphisms with coronary heart disease (CHD) in Han Chinese …
(LDLR gene) polymorphisms with coronary heart disease (CHD) in Han Chinese …
[HTML][HTML] Relationships between genetic polymorphisms of E670G in PCSK9 gene and coronary artery disease: a meta-analysis
D Adi, X Xie, F Liu, YT Ma… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Objective: Proprotein convertase subtilisin-like kexin type 9 (PCSK9) gene E670G
Polymorphism has been reported to be associated with coronary artery disease (CAD) and …
Polymorphism has been reported to be associated with coronary artery disease (CAD) and …
[HTML][HTML] E670G polymorphism of PCSK9 gene of patients with coronary heart disease among Han population in Hainan and three provinces in the northeast of China
XM He, L Chen, TS Wang, YB Zhang, JB Luo… - Asian Pacific journal of …, 2016 - Elsevier
Objective To investigate the correlation between E670G polymorphism of proprotein
convertase subtilisin/kexin type 9 (PCSK9) gene and coronary heart disease (CHD), and …
convertase subtilisin/kexin type 9 (PCSK9) gene and coronary heart disease (CHD), and …
A novel study to examine the association of PCSK9 rs505151 polymorphism and coronary artery disease in north Indian population
S Reddy, N Kaur, J Singh - Journal of genetics, 2018 - Springer
There is a drastic increase in the number of people suffering from coronary artery disease
(CAD) worldwide with Indians being no exception. Being a developing country and …
(CAD) worldwide with Indians being no exception. Being a developing country and …
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