[PDF][PDF] A pan-cancer single-cell panorama of human natural killer cells
F Tang, J Li, L Qi, D Liu, Y Bo, S Qin, Y Miao, K Yu… - Cell, 2023 - cell.com
Natural killer (NK) cells play indispensable roles in innate immune responses against tumor
progression. To depict their phenotypic and functional diversities in the tumor …
progression. To depict their phenotypic and functional diversities in the tumor …
[HTML][HTML] Role of distinct natural killer cell subsets in anticancer response
Natural killer (NK) cells, the prototypic member of innate lymphoid cells, are important
effectors of anticancer immune response. These cells can survey and control tumor initiation …
effectors of anticancer immune response. These cells can survey and control tumor initiation …
[HTML][HTML] Cytokines orchestrating the natural killer-myeloid cell crosstalk in the tumor microenvironment: implications for natural killer cell-based cancer immunotherapy
S Gaggero, K Witt, M Carlsten, S Mitra - Frontiers in immunology, 2021 - frontiersin.org
Natural killer (NK) cells are endowed with germline-encoded receptors that enable them to
detect and kill malignant cells without prior priming. Over the years, overwhelming evidence …
detect and kill malignant cells without prior priming. Over the years, overwhelming evidence …
The cancer–natural killer cell immunity cycle
ND Huntington, J Cursons, J Rautela - Nature Reviews Cancer, 2020 - nature.com
Immunotherapy with checkpoint blockade induces rapid and durable immune control of
cancer in some patients and has driven a monumental shift in cancer treatment. Neoantigen …
cancer in some patients and has driven a monumental shift in cancer treatment. Neoantigen …
NK cells and cancer: you can teach innate cells new tricks
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic
function that provide host defence against microbial infection and tumours. Here, we review …
function that provide host defence against microbial infection and tumours. Here, we review …
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy
NK Wolf, DU Kissiov, DH Raulet - Nature Reviews Immunology, 2023 - nature.com
Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …
[HTML][HTML] Therapeutic potential and challenges of natural killer cells in treatment of solid tumors
A Gras Navarro, AT Björklund, M Chekenya - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are innate lymphoid cells that hold tremendous potential for effective
immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring …
immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring …
[HTML][HTML] Natural killer cells in cancer biology and therapy
SY Wu, T Fu, YZ Jiang, ZM Shao - Molecular cancer, 2020 - Springer
The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …
an important hallmark of cancer, largely contributing to tumor progression and metastasis …
[HTML][HTML] Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions
J Russick, PE Joubert, M Gillard-Bocquet… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through
their cytotoxic effector functions and their capacity to interact with other immune cells to build …
their cytotoxic effector functions and their capacity to interact with other immune cells to build …
[HTML][HTML] Natural killer cells: the linchpin for successful cancer immunotherapy
KA Shaver, TJ Croom-Perez, AJ Copik - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy is a highly successful and rapidly evolving treatment modality that
works by augmenting the body's own immune system. While various immune stimulation …
works by augmenting the body's own immune system. While various immune stimulation …