Reduced calorie intake is a religious and medical practice known since very old times, but
its direct influence on life span in all organisms, included humans, has been demonstrated …

Resveratrol (RESV) exerts important pharmacological effects on human health: in addition to
its beneficial effects on type 2 diabetes and cardiovascular diseases, it also modulates …

The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the
recent years, this compound received renewed interest as several findings implicated …

Aging is linked to a time-associated decline in both cellular function and repair capacity
leading to malfunction on an organismal level, increased frailty, higher incidence of …

Studies show that the plant polyphenol resveratrol can extend the life span of yeast, worms,
flies, and fish. It also mitigates the metabolic dysfunction of mice fed high-fat diets …

Aging is characterized by a progressive deterioration of physiological functions and
metabolic processes. Healthy aging remains one of the ideals of modern society. In aging …

Resveratrol (RSV) is a naturally occurring polyphenolic compound endowed with interesting
biological properties/functions amongst which are its activity as an antioxidant and as Sirtuin …

Ageing is a plastic process and can be successfully modulated by some biomedical
approaches or pharmaceutics. In this manner it is possible to delay or even prevent some …

Resveratrol improves healthspan and lifespan in many organisms. Several different targets
and mechanisms of action have been proposed to explain the beneficial effects of …

Background: Sirtuin 1–7 (SIRT1–7) are deacetylases that are dependent on NAD+ for their
activity. SIRT1 down-regulates p53 activity, increasing lifespan, cell survival, and …