Transforming growth factor beta1 (TGFbeta1) in physiology and pathology

D Kajdaniuk, B Marek, H Borgiel-Marek… - Endokrynologia …, 2013 - journals.viamedica.pl
This review describes precisely the consequence of TGFβ1 prevalence in the organism, and
its significant influence on physiological and pathophysiological processes. Organ and …

TGF-beta (transforming growth factor-beta) in chronic inflammatory conditions-a new diagnostic and prognostic marker

A Marek, J Brodzicki, A Liberek, M Korzon - Med Sci Monit, 2002 - medscimonit.com
TGF-β is a cytokine with varied properties and pleiotropic activity. It is released in an inactive
form. To exhibit its biological activity, it requires binding to extracellular matrix proteins and …

TGF‐β signalling and liver disease

I Fabregat, J Moreno‐Càceres, A Sánchez… - The FEBS …, 2016 - Wiley Online Library
The transforming growth factor‐beta (TGF‐β) family signalling pathways play essential roles
in the regulation of different cellular processes, including proliferation, differentiation …

[PDF][PDF] Roles of TGF-beta in hepatic fibrosis

AM Gressner, R Weiskirchen, K Breitkopf, S Dooley - Front Biosci, 2002 - academia.edu
Transforming Growth Factor-beta in the Liver: Structure, Processing and Function 3. TGF-
beta Signal Transduction in Liver Cells 4. Hepatic Stellate Cell Activation 5. TGF-beta and …

Circulating transforming growth factor β1as an indicator of hepatic function impairment in liver cirrhosis

R Flisiak, B Pytel-Krolczuk, D Prokopowicz - Cytokine, 2000 - Elsevier
In the liver, transforming growth factor (TGF)-β1is primarily responsible for activation of fat-
storing cells, which are the main source of extracellular matrix proteins. Their deposition play …

[HTML][HTML] Pathobiology of transforming growth factor β in cancer, fibrosis and immunologic disease, and therapeutic considerations

GJ Prud'Homme - Laboratory investigation, 2007 - Elsevier
Transforming growth factor β (TGF-β) is a highly pleiotropic cytokine that plays an important
role in wound healing, angiogenesis, immunoregulation and cancer. The cells of the …

[HTML][HTML] TGF-β in progression of liver disease

S Dooley, P Ten Dijke - Cell and tissue research, 2012 - Springer
Transforming growth factor-β (TGF-β) is a central regulator in chronic liver disease
contributing to all stages of disease progression from initial liver injury through inflammation …

Emerging insights into transforming growth factor β Smad signal in hepatic fibrogenesis

Y Inagaki, I Okazaki - Gut, 2007 - gut.bmj.com
BACKGROUND TGFβ is a member of a large family of pleiotropic cytokines that includes
bone morphogenetic proteins (BMPs), activins and other related factors. Mammals have …

Parenchymal transforming growth factor beta‐1: its type II receptor and Smad signaling pathway correlate with inflammation and fibrosis in chronic liver disease of viral …

F Calabrese, M Valente, C Giacometti… - Journal of …, 2003 - Wiley Online Library
Abstract Background and Aims: Transforming growth factor‐beta (TGF‐beta) system is
involved in the control of cell growth and extracellular matrix formation. Previous studies in …

Localization of transforming growth factor β1 and its latent binding protein in human chronic pancreatitis

JL Van Laethem, J Deviere, A Resibois, F Rickaert… - Gastroenterology, 1995 - Elsevier
Background/Aims: Transforming growth factor β1 (TGF-β1) is thought to be the mediator of
fibrosis in liver, glomerular, and pulmonary fibrosis. This study investigated the expression of …