Pharmacokinetics of Quercetin‐Loaded Methoxy Poly (ethylene glycol)‐b‐poly (L‐lactic acid) Micelle after Oral Administration in Rats
L Lv, C Liu, Z Li, F Song, G Li… - BioMed Research …, 2017 - Wiley Online Library
The purpose of this study was to evaluate the potential of micelle to change the
pharmacokinetics of quercetin (QUT), with a primary goal of enhancing its oral …
pharmacokinetics of quercetin (QUT), with a primary goal of enhancing its oral …
Enhancing oral bioavailability of quercetin using novel soluplus polymeric micelles
L Dian, E Yu, X Chen, X Wen, Z Zhang, L Qin… - Nanoscale research …, 2014 - Springer
To improve its poor aqueous solubility and stability, the potential chemotherapeutic drug
quercetin was encapsulated in soluplus polymeric micelles by a modified film dispersion …
quercetin was encapsulated in soluplus polymeric micelles by a modified film dispersion …
Preparation and in vitro and in vivo evaluation of quercetin-loaded mixed micelles for oral delivery
Quercetin (QT) is a plant polyphenol with various pharmacological properties. However, the
low water solubility limits its therapeutic efficacy. In the present study, QT-loaded sodium …
low water solubility limits its therapeutic efficacy. In the present study, QT-loaded sodium …
Formulation and in vitro evaluation of quercetin loaded polymeric micelles composed of pluronic P123 and Da-tocopheryl polyethylene glycol succinate
L Zhao, Y Shi, S Zou, M Sun, L Li… - Journal of biomedical …, 2011 - ingentaconnect.com
The objective of this study was to develop a polymeric delivery system to improve the
solubility and biological activity of Quercetin (QT). QT loaded mixed micelles, composed of …
solubility and biological activity of Quercetin (QT). QT loaded mixed micelles, composed of …
Development of quercetin nanoformulation and in vivo evaluation using streptozotocin induced diabetic rat model
D Chitkara, SK Nikalaje, A Mittal, M Chand… - Drug delivery and …, 2012 - Springer
Quercetin-loaded poly (lactic-co-glycolic acid)(PLGA) nanoparticles (Qu-NP) were prepared
by emulsion–diffusion–evaporation method and characterized as 179.9±11.2 nm in size with …
by emulsion–diffusion–evaporation method and characterized as 179.9±11.2 nm in size with …
Polymer type and molecular weight dictate the encapsulation efficiency and release of Quercetin from polymeric micelles
S Sunoqrot, A Alsadi, O Tarawneh… - Colloid and Polymer …, 2017 - Springer
Flavonoids such as quercetin (QCT) represent a diverse class of natural compounds with
unique therapeutic potential in cancer and inflammatory diseases. However, their clinical …
unique therapeutic potential in cancer and inflammatory diseases. However, their clinical …
Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo …
LC Chen, YC Chen, CY Su, CS Hong… - International Journal …, 2016 - Taylor & Francis
Quercetin (Que) is known to have biological benefits including an anticancer effect, but low
water solubility limits its clinical application. The aim of this study was to develop a lecithin …
water solubility limits its clinical application. The aim of this study was to develop a lecithin …
Lecithin-Stabilized Polymeric Micelles (LsbPMs) for Delivering Quercetin: Pharmacokinetic Studies and Therapeutic Effects of Quercetin Alone and in Combination …
CE Chang, CM Hsieh, SC Huang, CY Su, MT Sheu… - Scientific reports, 2018 - nature.com
In this study, lecithin-stabilized polymeric micelles (L sb PMs) were prepared to load
quercetin (QUE) in order to improve its bioavailability and increase its antitumor activity. Its …
quercetin (QUE) in order to improve its bioavailability and increase its antitumor activity. Its …
Rp-HPLC determination of quercetin in a novel D-α-tocopherol polyethylene glycol 1000 succinate based SNEDDS formulation: Pharmacokinetics in Rat Plasma
Despite its proven efficacy in diverse metabolic disorders, quercetin (QU) for clinical use is
still limited because of its low bioavailability. D-α-Tocopherol polyethylene glycol 1000 …
still limited because of its low bioavailability. D-α-Tocopherol polyethylene glycol 1000 …
Comparative Serum and Brain Pharmacokinetics of Quercetin after Oral and Nasal Administration to Rats as Lyophilized Complexes with β-Cyclodextrin Derivatives …
K Manta, P Papakyriakopoulou, A Nikolidaki, E Balafas… - Pharmaceutics, 2023 - mdpi.com
Quercetin (Que) is one of the most studied flavonoids with strong antioxidant properties
ascribed to its ability to bind free radicals and inactivate them. However, the low solubility of …
ascribed to its ability to bind free radicals and inactivate them. However, the low solubility of …
相关搜索
- lactic acid methoxy poly
- ethylene glycol methoxy poly
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- ethylene glycol oral administration
- pharmacokinetics and biodistribution oral delivery
- mixed micelles oral delivery
- polyethylene glycol rat plasma
- wistar rats oral delivery
- polyethylene glycol rp hplc
- release of quercetin polymeric micelles
- polyethylene glycol snedds formulation
- polyethylene glycol pluronic p123
- polyethylene glycol α tocopherol
- pharmacokinetics and biodistribution wistar rats