The recent deluge of genome-wide technologies for the mapping of the epigenome and
resulting data in cancer samples has provided the opportunity for gaining insights into and …

Advances in high-throughput, genome-wide profiling technologies have allowed for an
unprecedented view of the cancer genome landscape. Specifically, high-density microarrays …

DNA microarrays have been widely applied to the study of human cancer, delineating
myriad molecular subtypes of cancer, many of which are associated with distinct biological …

Deep learning is a subdiscipline of artificial intelligence that uses a machine learning
technique called artificial neural networks to extract patterns and make predictions from …

Recent molecular and genetic studies have revealed the importance of DNA methylation, a
key epigenetic mark, in regulating gene expression and the abnormal profiles of DNA …

Cancer is a complex disease with a large financial and healthcare burden on society. One
hallmark of the disease is the uncontrolled growth and proliferation of malignant cells. Unlike …

Accurate detection of epimutations in tumor cells is crucial for understanding the molecular
pathogenesis of cancer. Alterations in DNA methylation in cancer are functionally important …

Cancer is a complex disease, driven by aberrant activity in numerous signaling pathways in
even individual malignant cells. Epigenetic changes are critical mediators of these functional …

Background Genomics has substantially changed our approach to cancer research. Gene
expression profiling, for example, has been utilized to delineate subtypes of cancer, and …

High-throughput DNA sequencing has revolutionized the study of cancer genomics with
numerous discoveries that are relevant to cancer diagnosis and treatment. The latest …