Enhanced synergistic antibacterial and antibiofilm efficacy of main-chain polysulfoniums with antibiotics by balancing charge density and amphiphilicity
Y Zhao, X Wang, Y Hu, J Zhao, M Sun… - ACS Applied Polymer …, 2023 - ACS Publications
Infection diseases caused by Gram-negative pathogens are exceedingly difficult to treat
because their characteristic outer membrane limits antibiotic entry. Herein, we report the …
because their characteristic outer membrane limits antibiotic entry. Herein, we report the …
Effect of Chain Lengths on the Antibiofilm and Hemolytic Activities of Main-Chain Alternating Polysulfoniums
Y Hu, J Zhao, M Yang, X Wang, H Zhang… - ACS Applied Polymer …, 2022 - ACS Publications
Unlike antibiotics with accurate chemical structures, polydisperse chain lengths of synthetic
polycations usually result in undesirable variations of antibacterial performance, which …
polycations usually result in undesirable variations of antibacterial performance, which …
Main-chain sulfonium-containing homopolymers with negligible hemolytic toxicity for eradication of bacterial and fungal biofilms
X Wang, G Wang, J Zhao, Z Zhu, J Rao - ACS Macro Letters, 2021 - ACS Publications
Antimicrobials against planktonic cells and established biofilms at low doses are in
increasing demand to tackle antibiotic-resistant biofilm infections. As a promising alternative …
increasing demand to tackle antibiotic-resistant biofilm infections. As a promising alternative …
Broad-spectrum bactericidal activity and remarkable selectivity of main-chain sulfonium-containing polymers with alternating sequences
Y Hu, J Zhao, J Zhang, Z Zhu, J Rao - ACS Macro Letters, 2021 - ACS Publications
Incorporation of cationic groups into polymers represents one of the most widely used
strategies to prepare antibacterial materials. Sulfonium, as a typical cationic moiety, displays …
strategies to prepare antibacterial materials. Sulfonium, as a typical cationic moiety, displays …
High antibacterial activity and selectivity of the versatile polysulfoniums that combat drug resistance
J Sun, M Li, M Lin, B Zhang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Sulfonium‐ion‐containing polymers exhibit significant potential benefits for various
applications. An efficient strategy to synthesize a type of antibacterial sulfonium‐ion‐bearing …
applications. An efficient strategy to synthesize a type of antibacterial sulfonium‐ion‐bearing …
Inherently self-sterilizing charged multiblock polymers that kill drug-resistant microbes in minutes
BST Peddinti, F Scholle, MG Vargas, SD Smith… - Materials …, 2019 - pubs.rsc.org
Drug-resistant microbes loom as a growing threat to global healthcare by greatly increasing
the risk of hospital-acquired infections that could ultimately become fatal, especially for …
the risk of hospital-acquired infections that could ultimately become fatal, especially for …
pH window for high selectivity of ionizable antimicrobial polymers toward bacteria
Y Geng, Y Yuan, Y Bao, S Huang, X Wang… - … Applied Materials & …, 2023 - ACS Publications
Antimicrobial polymers exhibit great potential for treating drug-resistant bacteria; however,
designing antimicrobial polymers that can selectively kill bacteria and cause relatively low …
designing antimicrobial polymers that can selectively kill bacteria and cause relatively low …
Main-chain polysulfonium salts: development of non-ammonium antibacterial polymers similar in their activity to antibiotic drugs vancomycin and kanamycin
J Oh, A Khan - Biomacromolecules, 2021 - ACS Publications
Typically, quaternary ammonium polymers are employed for antibacterial purposes.
However, a century of use has led bacteria to develop resistance to such materials …
However, a century of use has led bacteria to develop resistance to such materials …
Ammonium, Phosphonium, and Sulfonium Polymers for Antimicrobial Applications: A Comparative Study
Cationic polymers have gained significant attention as potent antimicrobial agents due to the
emergence of antibiotic resistance. These polymers can interact with the negatively charged …
emergence of antibiotic resistance. These polymers can interact with the negatively charged …
Functionalized polymers enhance permeability of antibiotics in gram‐negative MDR bacteria and biofilms for synergistic antimicrobial therapy
A Gupta, JMV Makabenta, F Schlüter… - Advanced …, 2020 - Wiley Online Library
The emergence of multidrug‐resistant (MDR) pathogenic bacteria constitutes a key threat to
global health. Infections caused by multidrug‐resistant Gram‐negative bacteria are …
global health. Infections caused by multidrug‐resistant Gram‐negative bacteria are …