[HTML][HTML] Combination of CRAFITY score with Alpha-fetoprotein response predicts a favorable outcome of atezolizumab plus bevacizumab for unresectable …

W Teng, CC Lin, CW Su, PT Lin, YC Hsieh… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) with atezolizumab plus bevacizumab are promising
agents for unresectable hepatocellular carcinoma (HCC). We tried to guide the treatment …

Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus …

T Hatanaka, S Kakizaki, A Hiraoka, T Tada… - Hepatology …, 2022 - Springer
Aim This study aimed to investigate the utility of C-reactive protein (CRP) and alpha-
fetoprotein (AFP) in immunotherapy (CRAFITY) score in hepatocellular carcinoma (HCC) …

Predictive biomarkers of survival in patients with advanced hepatocellular carcinoma receiving atezolizumab plus bevacizumab treatment

YE Chon, J Cheon, H Kim, B Kang, Y Ha… - Cancer …, 2023 - Wiley Online Library
Background Since atezolizumab plus bevacizumab (ATE+ BEV) regimen for patients with
unresectable hepatocellular carcinoma (HCC) was released quite recently, real‐world data …

α‐FAtE: A new predictive score of response to atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma

F Rossari, T Tada, G Suda, S Shimose… - … Journal of Cancer, 2024 - Wiley Online Library
Atezolizumab plus bevacizumab (AB) and lenvatinib can be alternatively used as first‐line
systemic treatment of unresectable hepatocellular carcinoma (HCC). However, no direct …

[PDF][PDF] Alpha-fetoprotein as a potential surrogate biomarker for atezolizumab+ bevacizumab treatment of hepatocellular carcinoma

AX Zhu, F Dayyani, CJ Yen, Z Ren, Y Bai, Z Meng… - Clinical Cancer …, 2022 - AACR
Purpose: Atezolizumab+ bevacizumab is the new standard of care for systemic treatment-
naive, unresectable hepatocellular carcinoma (HCC). This exploratory study investigated on …

Evaluation of response to atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma using the combination of response evaluation criteria …

T Kinami, K Amioka, T Kawaoka, S Uchikawa… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is reportedly the fifth most common
malignancy in the world. Atezolizumab plus bevacizumab combination therapy (Atezo+ …

Early tumor response and safety of atezolizumab plus bevacizumab for patients with unresectable hepatocellular carcinoma in real-world practice

Y Ando, T Kawaoka, M Kosaka, Y Shirane, Y Johira… - Cancers, 2021 - mdpi.com
Simple Summary Although atezolizumab plus bevacizumab combination therapy was
approved in September 2020 as the first immune-combined therapy for hepatocellular …

Early prediction of response focused on tumor markers in atezolizumab plus bevacizumab therapy for hepatocellular carcinoma

N Tanabe, I Saeki, Y Aibe, T Matsuda, T Hanazono… - Cancers, 2023 - mdpi.com
Simple Summary The combination of atezolizumab and bevacizumab was introduced as a
first-line therapy for patients with unresectable hepatocellular carcinoma in 2020. Although …

Optimal threshold of alpha-fetoprotein response in patients with unresectable hepatocellular carcinoma treated with atezolizumab and bevacizumab

N Tamaki, T Tada, M Kurosaki, Y Yasui, H Ochi… - Investigational New …, 2022 - Springer
Summary Alpha-fetoprotein (AFP) response (relative decline in AFP) is associated with
imaging response evaluated by response evaluation criteria in solid tumors ver1. 1 …

Therapeutic efficacy and safety of lenvatinib after atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma

S Yano, T Kawaoka, S Yamasaki, Y Johira, M Kosaka… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitor therapy has been rapidly developed for the
treatment of unresectable hepatocellular carcinoma (HCC). In the IMbrave150 trial …