Study on COX-2 Expression and Signalling Pathway in HUVECs Induced by P. gingivalis Lipopolysaccharide

Y GAO, J LI, W LI - Journal of Oral Science Research, 2022 - manu45.magtech.com.cn
Objective: To study the effect of P. gingivalis lipopolysaccharide on Cyclooxygenase-2 (Cox-
2) expression in human umbilical vein endothelial cells (HUVECs), and investigate whether …

Cyclooxygenase-2 induction in Porphyromonas gingivalis-infected THP-1 monocytic cells

EK Choi, BH Oh, IC Kang - International Journal of Oral Biology, 2006 - koreascience.kr
Periodontopathogens including Porphyromonas gingivalis interact with host periodontal
cells and the excessive subsequent host responses contribute a major part to the …

[HTML][HTML] Celecoxib suppresses lipopolysaccharide‑stimulated oral squamous cell carcinoma proliferation in vitro and in vivo

H Yoshida, H Yoshimura, S Matsuda… - Oncology …, 2019 - spandidos-publications.com
Periodontitis is one of the most common chronic oral inflammatory conditions worldwide and
is associated with a risk of developing oral squamous cell carcinoma (OSCC) …

Prostaglandin production via induction of cyclooxygenase-2 by human gingival fibroblasts stimulated with lipopolysaccharides

K Noguchi, M Shitashige, M Yanai, I Morita, T Nishihara… - Inflammation, 1996 - Springer
The purpose of the present study was to investigate the involvement of cyclooxygenase-1
(COX-1) and cyclooxygenase-2 (COX-2) in PGE 2 production by human gingival fibroblasts …

[HTML][HTML] Inducing cyclooxygenase-2 expression, prostaglandin E2 and prostaglandin F2α production of human dental pulp cells by activation of toll-like receptor-3 …

MC Chang, JH Wu, SY Chen, YT Hsu, SY Yeung… - Journal of Dental …, 2024 - Elsevier
Background/purpose Bacterial infection was the major etiology for pulpal/root canal
infection. This study aimed to investigate the activation of toll-like receptor-3 (TLR) on …

Nicotine and lipopolysaccharide stimulate the production of MMPs and prostaglandin E2 by hypoxia‐inducible factor‐1α up‐regulation in human periodontal ligament …

YS Kim, SI Shin, KL Kang, JH Chung… - Journal of …, 2012 - Wiley Online Library
Kim Y‐S, Shin S‐I, Kang K‐L, Herr Y, Bae W‐J, Kim E‐C. Nicotine and lipopolysaccharide
stimulate the production of MMPs and prostaglandin E2 by hypoxia‐inducible factor‐1α up …

Immuno-localization of COX-1 and COX-2 in the rat molar periodontal tissue after topical application of lipopolysaccharide

M Miyauchi, M Hiraoka, H Oka, S Sato, Y Kudo… - Archives of Oral …, 2004 - Elsevier
Up-regulation of prostaglandin E2 (PGE2) production in the periodontal tissue is considered
to be important for periodontal tissue destruction. The purpose of the study was to …

Effect of Porphyromonas gingivalis lipopolysaccharide on induced secretion of inflammatory cytokines by different cell lines

YF Chen, J Yan, DY Zhang, LL Chen - Zhejiang da xue xue bao. Yi …, 2008 - europepmc.org
Objective To determine the effect of Porphyromonas gingivalis lipopolysaccharide (LPS) on
induced secretion of inflammatory cytokines by different cell lines. Methods LPS of P …

[HTML][HTML] Modulation of proinflammatory mediators by viruses-bacteria synergism in human osteoblasts-an in vitro study

YY Lee, MJ Li, ZY Yu, SL Hung - Journal of the Formosan Medical …, 2022 - Elsevier
Background/Purpose Viruses-bacteria synergistic interaction is associated with destructive
periodontal diseases. However, the underlying mechanism for tissue destruction is not fully …

Curcumin attenuates cyclooxygenase‐2 expression via inhibition of the NF‐κB pathway in lipopolysaccharide‐stimulated human gingival fibroblasts

P Hu, P Huang, MW Chen - Cell biology international, 2013 - Wiley Online Library
Porphyromonas gingivalis lipopolysaccharide (LPS) induces the expression of the
cyclooxygenase‐2 (COX‐2), which contributes to the process of periodontitis. Curcumin, a …