Cyclophosphamide inhibits antibody-dependent cellular cytotoxicity (ADCC) suppression exerted by lymph node cells

MS Palermo, M Giordano, S Olabuenaga, MA Isturiz - Cellular immunology, 1985 - Elsevier
Abstract The effect of Cyclophosphamide (Cy) on suppression of antibody-dependent
cellular Cytotoxicity (ADCC) by lymph node cells (LNC) was evaluated. The results show …

The effects of cyclophosphamide on antibody dependent cell-mediated cytotoxicity in mice

M Giordano, MA Isturiz, L Colombo - Journal of …, 1982 - Taylor & Francis
The effect of cyclophosphamide (CY) on antibody dependent cell-mediated cytotoxicity
(ADCC) was evaluated. The results indicated that a single injection of CY markedly …

The influence of cyclophosphamide on antibody formation in the mouse.

JM Willers, E Sluis - Annales D'immunologie, 1975 - europepmc.org
A single injection of cyclophosphamide (CY)(300 mg/kg) 8 h prior to immunization results in
a complete suppression of the antibody formation in mice. The effect of CY on the number …

Genetic differences in the cyclophosphamide-induced immune suppression: Weaker suppression of T-cell cytotoxicity by cyclophosphamide activated by CBA mice

M Hurme, BE Bång, M Sihvola - Clinical Immunology and …, 1980 - Elsevier
Cyclophosphamide (Cy), an alkylating agent, has widely been used as an
immunosuppressive drug both in clinical medicine and experimental immunology. This …

Cyclophosphamide augments ADCC by increasing the expression of Fc-receptors

MS Palermo, M Giordano, GP Serebrinsky, JR Geffner… - Immunology letters, 1987 - Elsevier
Previous reports demonstrated that cyclophosphamide (Cy) enhances two Fcγ receptor
(FcγR) mediated functions: antibody-dependent cellular cytotoxicity (ADCC) and …

Cyclophosphamide-induced suppressor cells in nude mice

M Shimizu, D Sabolovic, H Ozawa, T Iwaguchi - Anti-cancer drugs, 1992 - journals.lww.com
Lymphocytes regenerated after treatment with a high dose of cyclophosphamide (CY) were
characterized in nude mice. Ten days after a single injection of 200 mg/kg CY into nude …

The effects of cyclophosphamide on mitogen-induced and antibody-dependent cellular cytotoxicity in guinea pigs

A Winkelstein, JA Brizzi, BL Kift - Journal of Immunopharmacology, 1979 - Taylor & Francis
Lymph node cells from normal guinea pigs, when stimulated with the non-specific mitogen
PHA were transformed to activated killer cells, capable of lysing 51Cr labeled mouse …

[HTML][HTML] Mechanisms of immunosuppression: effects of cyclophosphamide on cellular immunity

A Winkelstein - Blood, 1973 - Elsevier
A course of cyclophosphamide administered to guinea pigs after immunization with
mycobacteria led to a transient inhibition of cutaneous hypersensitivity to tuberculin protein …

Inhibition of in vitro antibody synthesis by cyclophosphamide-induced suppressor cells

VL Braciale, CR Parish - Cellular Immunology, 1980 - Elsevier
A population of suppressor lymphocytes appears in the spleens of mice 5 to 14 days after
treatment with a high dose of cyclophosphamide (100–200 mg/kg body wt). Removal of …

Enhancing effect of low dose cyclophosphamide treatment on the in vitro antibody response

HL Duclos, P Galanaud, O Devinsky… - European journal of …, 1977 - Wiley Online Library
We have studied the effect of cyclophosphamide (CY) administration on the subsequent in
vitro antibody response in the mouse. Treatment with a low dose (20 mg/kg) of CY four days …