Engineering Gut Symbionts: A Way to Promote Bee Growth?

P Sattayawat, S Inwongwan, N Noirungsee, J Li, J Guo… - Insects, 2024 - mdpi.com
Simple Summary Bees are important pollinators that play a role in balancing ecosystems;
however, their survival rates have decreased due to many factors, including pathogens and …

[HTML][HTML] Single-step genome engineering in the bee gut symbiont Snodgrassella alvi

PJ Lariviere, AHMZ Ashraf, SP Leonard, LG Miller… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Honey bees are economically relevant pollinators experiencing population declines due to a
number of threats. As in humans, the health of bees is influenced by their microbiome. The …

Engineering insects from the endosymbiont out

KM Elston, SP Leonard, P Geng, SB Bialik… - Trends in …, 2022 - cell.com
Insects are an incredibly diverse group of animals with species that benefit and harm natural
ecosystems, agriculture, and human health. Many insects have consequential associations …

Engineering a symbiont as a biosensor for the honey bee gut environment

A Chhun, S Moriano-Gutierrez, F Zoppi, A Cabirol… - bioRxiv, 2023 - biorxiv.org
The honey bee is a powerful model system to probe host-gut microbiota interactions, and an
important pollinator species for natural ecosystems and for agriculture. While bacterial …

An engineered bacterial symbiont allows noninvasive biosensing of the honey bee gut environment

A Chhun, S Moriano-Gutierrez, F Zoppi, A Cabirol… - Plos …, 2024 - journals.plos.org
The honey bee is a powerful model system to probe host–gut microbiota interactions, and an
important pollinator species for natural ecosystems and for agriculture. While bacterial …

Genetic engineering of bee gut microbiome bacteria with a toolkit for modular assembly of broad-host-range plasmids

SP Leonard, J Perutka, JE Powell, P Geng… - ACS synthetic …, 2018 - ACS Publications
Engineering the bacteria present in animal microbiomes promises to lead to breakthroughs
in medicine and agriculture, but progress is hampered by a dearth of tools for genetically …

Engineered gut symbiont inhibits microsporidian parasite and improves honey bee survival

Q Huang, PJ Lariviere, JE Powell… - Proceedings of the …, 2023 - National Acad Sciences
Honey bees (Apis mellifera) are critical agricultural pollinators as well as model organisms
for research on development, behavior, memory, and learning. The parasite Nosema …

Honey bee (Apis mellifera) gut microbiota promotes host endogenous detoxification capability via regulation of P450 gene expression in the digestive tract

Y Wu, Y Zheng, Y Chen, S Wang, Y Chen… - Microbial …, 2020 - Wiley Online Library
There is growing number of studies demonstrating a close relationship between insect gut
microbiota and insecticide resistance. However, the contribution of the honey bee gut …

Evolution of host specialization in gut microbes: the bee gut as a model

WK Kwong, NA Moran - Gut microbes, 2015 - Taylor & Francis
Bacterial symbionts of eukaryotes often give up generalist lifestyles to specialize to particular
hosts. The eusocial honey bees and bumble bees harbor two such specialized gut …

Rational engineering of a synthetic insect-bacterial mutualism

Y Su, HC Lin, LS Teh, F Chevance, I James, C Mayfield… - Current Biology, 2022 - cell.com
Many insects maintain mutualistic associations with bacterial endosymbionts, but little is
known about how they originate in nature. In this study, we describe the establishment and …