Novel avenues to approach non-CPAP therapy and implement comprehensive obstructive sleep apnoea care

JL Pépin, P Eastwood, DJ Eckert - European Respiratory …, 2022 - Eur Respiratory Soc
Recent advances in obstructive sleep apnoea (OSA) pathophysiology and translational
research have opened new lines of investigation for OSA treatment and management. Key …

Obstructive sleep apnea: personalizing CPAP alternative therapies to individual physiology

B Nokes, J Cooper, M Cao - Expert Review of Respiratory …, 2022 - Taylor & Francis
Introduction The recent continuous positive airway pressure (CPAP) crisis has highlighted
the need for alternative obstructive sleep apnea (OSA) therapies. This article serves to …

From CPAP to tailored therapy for obstructive sleep apnoea

K Sutherland, K Kairaitis, BJ Yee, PA Cistulli - Multidisciplinary Respiratory …, 2018 - Springer
Abstract Obstructive Sleep Apnoea (OSA) is a common sleep disorder that is associated with
daytime symptoms and a range of comorbidity and mortality. Continuous Positive Airway …

Obstructive sleep apnea: current perspectives

AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …

Potential therapeutic targets in obstructive sleep apnoea

JP Saboisky, NL Chamberlin… - Expert opinion on …, 2009 - Taylor & Francis
Obstructive sleep apnoea (OSA) is a disease of ever-increasing importance due to its
association with multiple impairments and rising prevalence in an increasingly susceptible …

Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment

MR Bonsignore, MCS Giron, O Marrone… - European …, 2017 - Eur Respiratory Soc
In all fields of medicine, major efforts are currently dedicated to improve the clinical,
physiological and therapeutic understanding of disease, and obstructive sleep apnoea …

Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy

DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …

[HTML][HTML] Non-continuous positive airway pressure treatment options in obstructive sleep apnoea: a pathophysiological perspective

M Bosi, SI Parenti, A Sanna, G Plazzi, A De Vito… - Sleep Medicine …, 2021 - Elsevier
The phenotyping of the pathophysiology of obstructive sleep apnoea (OSA) lies at the core
of tailored treatments and it is one of the most debated topics in sleep medicine research …

Obstructive sleep apnea: transition from pathophysiology to an integrative disease model

WT McNicholas, D Pevernagie - Journal of Sleep Research, 2022 - Wiley Online Library
Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …

[HTML][HTML] Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review

WT McNicholas, H Korkalainen - Frontiers in Neurology, 2023 - frontiersin.org
Obstructive Sleep Apnea (OSA) arises due to periodic blockage of the upper airway (UA)
during sleep, as negative pressure generated during inspiration overcomes the force …