Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models
M Di Martile, S Garzoli, M Sabatino, E Valentini… - Cell death …, 2021 - nature.com
Essential oils (EOs) have been recently emerging for their promising biological activities in
preventing tumorigenesis or progression of different tumor histotypes, including melanoma …
preventing tumorigenesis or progression of different tumor histotypes, including melanoma …
[HTML][HTML] Induction of necrosis and cell cycle arrest in murine cancer cell lines by Melaleuca alternifolia (tea tree) oil and terpinen-4-ol
SJ Greay, DJ Ireland, HT Kissick, A Levy… - Cancer Chemotherapy …, 2010 - Springer
Purpose To examine the in vitro anticancer activity of Melaleuca alternifolia (tea tree) oil
(TTO), and its major active terpene component, terpinen-4-ol, against two aggressive murine …
(TTO), and its major active terpene component, terpinen-4-ol, against two aggressive murine …
Essential oils and their main chemical components: The past 20 years of preclinical studies in melanoma
M Di Martile, S Garzoli, R Ragno, D Del Bufalo - Cancers, 2020 - mdpi.com
Simple Summary In the last years, targeted therapy and immunotherapy modified the
landscape for metastatic melanoma treatment. These therapeutic approaches led to an …
landscape for metastatic melanoma treatment. These therapeutic approaches led to an …
A narrative review of the antitumor activity of monoterpenes from essential oils: An update
TQ Machado, ACC Da Fonseca… - BioMed research …, 2022 - Wiley Online Library
Monoterpenes are a group of natural products that have been widely studied due to their
therapeutic potential against various pathologies. These compounds are abundant in the …
therapeutic potential against various pathologies. These compounds are abundant in the …
Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells
MR Loizzo, R Tundis, F Menichini, AM Saab… - Cell …, 2008 - Wiley Online Library
Objectives: The purpose of this study was to evaluate cytotoxic activity of Platycladus
orientalis, Prangos asperula and Cupressus sempervirens ssp. pyramidalis essential oils …
orientalis, Prangos asperula and Cupressus sempervirens ssp. pyramidalis essential oils …
[HTML][HTML] Resveratrol analogue, trans-4, 4′-dihydroxystilbene (DHS), inhibits melanoma tumor growth and suppresses its metastatic colonization in lungs
The prevalence of melanoma and the lack of effective therapy for metastatic melanoma
warrant extensive and systematic evaluations of small molecules in cellular and pre-clinical …
warrant extensive and systematic evaluations of small molecules in cellular and pre-clinical …
[HTML][HTML] Terpinen-4-ol, the main component of Melaleuca alternifolia (tea tree) oil inhibits the in vitro growth of human melanoma cells
A Calcabrini, A Stringaro, L Toccacieli… - Journal of Investigative …, 2004 - Elsevier
The search for innovative therapeutic approaches based on the use of new substances is
gaining more interest in clinical oncology. In this in vitro study the potential anti-tumoral …
gaining more interest in clinical oncology. In this in vitro study the potential anti-tumoral …
Anticancer effect of terpenes: focus on malignant melanoma
P Wróblewska-Łuczka, J Cabaj, J Bargieł… - Pharmacological …, 2023 - Springer
Melanoma is a highly aggressive and life-threatening form of skin cancer that accounts for a
significant proportion of cancer-related deaths worldwide. Although conventional cancer …
significant proportion of cancer-related deaths worldwide. Although conventional cancer …
Plant-derived terpenoids: a promising tool in the fight against melanoma
P Kłos, D Chlubek - Cancers, 2022 - mdpi.com
Simple Summary Despite the numerous therapies, melanoma remains the deadliest of all
skin cancers; however, plant-derived terpenoids are defense molecules that have proven …
skin cancers; however, plant-derived terpenoids are defense molecules that have proven …
Exploring the potent anticancer activity of essential oils and their bioactive compounds: Mechanisms and prospects for future cancer therapy
F Mohamed Abdoul-Latif, A Ainane… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the leading causes of death worldwide, affecting millions of people each
year. Fortunately, the last decades have been marked by considerable advances in the field …
year. Fortunately, the last decades have been marked by considerable advances in the field …
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