Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

JB Michel, JL Martin-Ventura, J Egido… - Cardiovascular …, 2011 - academic.oup.com
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of
atherothrombosis, providing a unique human model of this disease. The pathogenesis of …

[HTML][HTML] The abdominal aortic aneurysm and intraluminal thrombus: current concepts of development and treatment

A Piechota-Polanczyk, A Jozkowicz… - Frontiers in …, 2015 - frontiersin.org
The pathogenesis of the abdominal aortic aneurysm (AAA) shows several hallmarks of
atherosclerotic and atherothrombotic disease, but comprises an additional, predominant …

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease

MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …

Mechanisms of abdominal aortic aneurysm formation

A Daugherty, LA Cassis - Current atherosclerosis reports, 2002 - Springer
Abdominal aortic aneurysms (AAA) are permanent dilations in the infra-renal area in which
the arterial tissue is characterized by inflammation and medial degeneration. AAAs are a …

Inflammation and cellular immune responses in abdominal aortic aneurysms

K Shimizu, RN Mitchell, P Libby - Arteriosclerosis, thrombosis, and …, 2006 - Am Heart Assoc
Expansion and rupture of abdominal aortic aneurysms (AAA) result in high morbidity and
mortality rates. Like stenotic atherosclerotic lesions, AAA accumulate inflammatory cells, but …

Aortic wall inflammation in the pathogenesis, diagnosis and treatment of aortic aneurysms

G Skotsimara, A Antonopoulos, E Oikonomou… - Inflammation, 2022 - Springer
The role of inflammation in the development of aortic aneurysms is emerging, along with the
potential diagnostic and therapeutical potential of this correlation. Abdominal aorta …

Abdominal aortic aneurysms: an autoimmune disease?

VP Jagadesham, DJA Scott, SR Carding - Trends in molecular medicine, 2008 - cell.com
Abdominal aortic aneurysms (AAAs) are a multifactorial degenerative vascular disorder. One
of the defining features of the pathophysiology of aneurysmal disease is inflammation …

[HTML][HTML] Abdominal aortic aneurysm: roles of inflammatory cells

Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

[HTML][HTML] Endothelial dysfunction in the pathogenesis of abdominal aortic aneurysm

E DeRoo, A Stranz, H Yang, M Hsieh, C Se, T Zhou - Biomolecules, 2022 - mdpi.com
Abdominal aortic aneurysm (AAA), defined as a focal dilation of the abdominal aorta beyond
50% of its normal diameter, is a common and potentially life-threatening vascular disease …

Immune cells and molecular mediators in the pathogenesis of the abdominal aortic aneurysm

KD Rizas, N Ippagunta, MD Tilson III - Cardiology in review, 2009 - journals.lww.com
Abdominal aortic aneurysm is a multifactorial disease with genetic risk factors and an
immunologic component. Immune cells, including macrophages, neutrophils, mast cells, B …