EffectorP 3.0: prediction of apoplastic and cytoplasmic effectors in fungi and oomycetes

J Sperschneider, PN Dodds - Molecular plant-microbe …, 2022 - Am Phytopath Society
Many fungi and oomycete species are devasting plant pathogens. These eukaryotic
filamentous pathogens secrete effector proteins to facilitate plant infection. Fungi and …

EffectorP: predicting fungal effector proteins from secretomes using machine learning

J Sperschneider, DM Gardiner, PN Dodds… - New …, 2016 - Wiley Online Library
Eukaryotic filamentous plant pathogens secrete effector proteins that modulate the host cell
to facilitate infection. Computational effector candidate identification and subsequent …

Evaluation of secretion prediction highlights differing approaches needed for oomycete and fungal effectors

J Sperschneider, AH Williams, JK Hane… - Frontiers in plant …, 2015 - frontiersin.org
The steadily increasing number of sequenced fungal and oomycete genomes has enabled
detailed studies of how these eukaryotic microbes infect plants and cause devastating …

Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0

J Sperschneider, PN Dodds… - Molecular plant …, 2018 - Wiley Online Library
Plant‐pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive
improvements to EffectorP, the first machine learning classifier for fungal effector prediction …

[HTML][HTML] Effector biology of biotrophic plant fungal pathogens: Current advances and future prospects

R Jaswal, K Kiran, S Rajarammohan, H Dubey… - Microbiological …, 2020 - Elsevier
The interaction of fungal pathogens with their host requires a novel invading mechanism
and the presence of various virulence-associated components responsible for promoting the …

Advances and challenges in computational prediction of effectors from plant pathogenic fungi

J Sperschneider, PN Dodds, DM Gardiner… - PLoS …, 2015 - journals.plos.org
Fungi occupy diverse environmental niches and many have evolved to live a pathogenic
lifestyle, causing devastating diseases in plants and animals. The interface between host …

Computational prediction of effector proteins in fungi: opportunities and challenges

H Sonah, RK Deshmukh, RR Bélanger - Frontiers in plant science, 2016 - frontiersin.org
Effector proteins are mostly secretory proteins that stimulate plant infection by manipulating
the host response. Identifying fungal effector proteins and understanding their function is of …

ApoplastP: prediction of effectors and plant proteins in the apoplast using machine learning

J Sperschneider, PN Dodds, KB Singh… - New …, 2018 - Wiley Online Library
The plant apoplast is integral to intercellular signalling, transport and plant–pathogen
interactions. Plant pathogens deliver effectors both into the apoplast and inside host cells …

A catalogue of the effector secretome of plant pathogenic oomycetes

S Kamoun - Annu. Rev. Phytopathol., 2006 - annualreviews.org
The oomycetes form a phylogenetically distinct group of eukaryotic microorganisms that
includes some of the most notorious pathogens of plants. Oomycetes accomplish parasitic …

LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell

J Sperschneider, AM Catanzariti, K DeBoer, B Petre… - Scientific reports, 2017 - nature.com
Pathogens secrete effector proteins and many operate inside plant cells to enable infection.
Some effectors have been found to enter subcellular compartments by mimicking host …