Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survival-and
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …

Publisher Summary The fact that nerve growth factor (NGF) is required for the survival of
specific neuronal populations (in the peripheral nervous system and sympathetic and neural …

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3
(NT-3) are small, basic, secretory proteins that allow the survival of specific neuronal …

Of all isolated neurotrophic molecules Nerve Growth Factor (NGF) is the only one with a fully
established physiological function, at least in the peripheral nervous system (see Thoenen …

Brain-derived neurotrophic factor (BDNF) is a 27-kDa basic protein of noncovalently linked
13.5-kD subunits related to nerve growth factor and is produced by the central nervous …

Although brain‐derived neurotrophic factor is the most abundant and widely distributed
neurotrophin in the nervous system, reproducible determinations of its levels have been …

Neurotrophic factors are important regulators of the development and maintenance of
vertebrate nervous systems (reviewed in Korsching, 1993; Eide et al., 1993); Farinas and …

A purified polyclonal antibody preparation was made against recombinant human brain‐
derived neurotrophic factor (BDNF) in guinea pig and characterized for use in …

Brain-derived neurotrophic factor (BDNF) which supports survival of and fiber outgrowth
from sensory neurons and retinal ganglion cells has recently been cloned. It is closely …

Recombinant human brain-derived neurotrophic factor (rhBDNF) and neurotrophin 3 (rhNT-
3), two recently cloned molecules closely related to nerve growth factor (NGF), were …