Heritability of autism spectrum disorders: a meta‐analysis of twin studies

B Tick, P Bolton, F Happé, M Rutter… - Journal of Child …, 2016 - Wiley Online Library
Background The etiology of Autism Spectrum Disorder (ASD) has been recently debated
due to emerging findings on the importance of shared environmental influences. However …

Genetic heritability and shared environmental factors among twin pairs with autism

J Hallmayer, S Cleveland, A Torres… - Archives of general …, 2011 - jamanetwork.com
Context Autism is considered the most heritable of neurodevelopmental disorders, mainly
because of the large difference in concordance rates between monozygotic and dizygotic …

Autism spectrum disorders and autistic traits: a decade of new twin studies

A Ronald, RA Hoekstra - … Journal of Medical Genetics Part B …, 2011 - Wiley Online Library
Researchers continue to pursue a better understanding of the symptoms, comorbidities, and
causes of autism spectrum disorders. In this article we review more than 30 twin studies of …

Heritability of autism spectrum disorder in a UK population-based twin sample

E Colvert, B Tick, F McEwen, C Stewart… - JAMA …, 2015 - jamanetwork.com
Importance Most evidence to date highlights the importance of genetic influences on the
liability to autism and related traits. However, most of these findings are derived from …

Lower birth weight indicates higher risk of autistic traits in discordant twin pairs

M Losh, D Esserman, H Anckarsäter… - Psychological …, 2012 - cambridge.org
BackgroundAutism spectrum disorder (ASD) is a neurodevelopmental disorder of complex
etiology. Although strong evidence supports the causal role of genetic factors, environmental …

On the nature of monozygotic twin concordance and discordance for autistic trait severity: a quantitative analysis

L Castelbaum, CM Sylvester, Y Zhang, Q Yu… - Behavior Genetics, 2020 - Springer
The characterizing features of autism spectrum disorder (ASD) are continuously distributed
in nature; however, prior twin studies have not systematically incorporated this knowledge …

Genetic heterogeneity between the three components of the autism spectrum: a twin study

A Ronald, F Happé, P Bolton, LM Butcher… - Journal of the American …, 2006 - Elsevier
OBJECTIVE: This study investigated the etiology of autistic-like traits in the general
population and the etiological overlap between the three aspects of the triad of impairments …

The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood

P Lichtenstein, E Carlström, M Råstam… - American Journal of …, 2010 - Am Psychiatric Assoc
Objective: Autism spectrum disorders are considered to be among the most heritable mental
disorders, a notion based on surprisingly sparse data from small clinical studies. Population …

Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study

S Lundström, A Reichenberg, J Melke… - Journal of Child …, 2015 - Wiley Online Library
Background Evidence from twin and molecular genetic studies is accumulating that Autism
Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is …

A Danish population-based twin study on autism spectrum disorders

C Nordenbæk, M Jørgensen, KO Kyvik… - European child & …, 2014 - Springer
Genetic epidemiological studies of Autism Spectrum Disorders (ASDs) based on twin pairs
ascertained from the population and thoroughly assessed to obtain a high degree of …