Shared genetics between classes of obesity and psychiatric disorders: A large-scale genome-wide cross-trait analysis

H Ding, M Ouyang, J Wang, M Xie, Y Huang… - Journal of …, 2022 - Elsevier
Aims Epidemiological studies demonstrate an association between classes of obesity and
psychiatric disorders, although little is known about shared genetics and causality of …

Mendelian randomization analyses identify bidirectional causal relationships of obesity with psychiatric disorders

W Chen, J Feng, S Jiang, J Guo, XL Zhang… - Journal of Affective …, 2023 - Elsevier
Background Obesity have been showed to be strongly associated with psychiatric disorders,
but the exact causality and the direction of the relationship remain inconclusive. Thus, we …

[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations

L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
Objective To conduct a genome-wide association study (GWAS) of anorexia nervosa and to
calculate genetic correlations with a series of psychiatric, educational, and metabolic …

Genetic neuropathology of obsessive psychiatric syndromes

AE Jaffe, A Deep-Soboslay, R Tao… - Translational …, 2014 - nature.com
Anorexia nervosa (AN), bulimia nervosa (BN) and obsessive-compulsive disorder (OCD) are
complex psychiatric disorders with shared obsessive features, thought to arise from the …

Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

L Duncan, Z Yilmaz, H Gaspar… - American journal of …, 2017 - Am Psychiatric Assoc
Objective: The authors conducted a genome-wide association study of anorexia nervosa
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …

One size does not fit all. Genomics differentiates among anorexia nervosa, bulimia nervosa, and binge‐eating disorder

C Hübel, M Abdulkadir, M Herle… - … Journal of Eating …, 2021 - Wiley Online Library
Objective Genome‐wide association studies have identified multiple genomic regions
associated with anorexia nervosa. No genome‐wide studies of other eating disorders, such …

Genome‐wide association analysis of eating disorder‐related symptoms, behaviors, and personality traits

V Boraska, OSP Davis, LF Cherkas… - American Journal of …, 2012 - Wiley Online Library
Eating disorders (EDs) are common, complex psychiatric disorders thought to be caused by
both genetic and environmental factors. They share many symptoms, behaviors, and …

Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity

LM García-Marín, AI Campos, PF Kho, NG Martin… - Human Genetics, 2021 - Springer
Objective In the present study, we sought to identify causal relationships between obesity
and other complex traits and conditions using a data-driven hypothesis-free approach that …

Shared genetics of psychiatric disorders and type 2 diabetes: a large-scale genome-wide cross-trait analysis

H Ding, M Xie, J Wang, M Ouyang, Y Huang… - Journal of Psychiatric …, 2023 - Elsevier
Background Individuals with psychiatric disorders have elevated rates of type 2 diabetes
comorbidity. Although little is known about the shared genetics and causality of this …

Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia …

L Bang, S Bahrami, G Hindley, OB Smeland… - Translational …, 2023 - nature.com
Anorexia nervosa (AN) is a heritable eating disorder (50–60%) with an array of commonly
comorbid psychiatric disorders and related traits. Although significant genetic correlations …