Shared genetics between classes of obesity and psychiatric disorders: A large-scale genome-wide cross-trait analysis
H Ding, M Ouyang, J Wang, M Xie, Y Huang… - Journal of …, 2022 - Elsevier
Aims Epidemiological studies demonstrate an association between classes of obesity and
psychiatric disorders, although little is known about shared genetics and causality of …
psychiatric disorders, although little is known about shared genetics and causality of …
Mendelian randomization analyses identify bidirectional causal relationships of obesity with psychiatric disorders
W Chen, J Feng, S Jiang, J Guo, XL Zhang… - Journal of Affective …, 2023 - Elsevier
Background Obesity have been showed to be strongly associated with psychiatric disorders,
but the exact causality and the direction of the relationship remain inconclusive. Thus, we …
but the exact causality and the direction of the relationship remain inconclusive. Thus, we …
[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations
L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
Objective To conduct a genome-wide association study (GWAS) of anorexia nervosa and to
calculate genetic correlations with a series of psychiatric, educational, and metabolic …
calculate genetic correlations with a series of psychiatric, educational, and metabolic …
Genetic neuropathology of obsessive psychiatric syndromes
Anorexia nervosa (AN), bulimia nervosa (BN) and obsessive-compulsive disorder (OCD) are
complex psychiatric disorders with shared obsessive features, thought to arise from the …
complex psychiatric disorders with shared obsessive features, thought to arise from the …
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa
Objective: The authors conducted a genome-wide association study of anorexia nervosa
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …
One size does not fit all. Genomics differentiates among anorexia nervosa, bulimia nervosa, and binge‐eating disorder
Objective Genome‐wide association studies have identified multiple genomic regions
associated with anorexia nervosa. No genome‐wide studies of other eating disorders, such …
associated with anorexia nervosa. No genome‐wide studies of other eating disorders, such …
Genome‐wide association analysis of eating disorder‐related symptoms, behaviors, and personality traits
Eating disorders (EDs) are common, complex psychiatric disorders thought to be caused by
both genetic and environmental factors. They share many symptoms, behaviors, and …
both genetic and environmental factors. They share many symptoms, behaviors, and …
Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity
Objective In the present study, we sought to identify causal relationships between obesity
and other complex traits and conditions using a data-driven hypothesis-free approach that …
and other complex traits and conditions using a data-driven hypothesis-free approach that …
Shared genetics of psychiatric disorders and type 2 diabetes: a large-scale genome-wide cross-trait analysis
H Ding, M Xie, J Wang, M Ouyang, Y Huang… - Journal of Psychiatric …, 2023 - Elsevier
Background Individuals with psychiatric disorders have elevated rates of type 2 diabetes
comorbidity. Although little is known about the shared genetics and causality of this …
comorbidity. Although little is known about the shared genetics and causality of this …
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia …
Anorexia nervosa (AN) is a heritable eating disorder (50–60%) with an array of commonly
comorbid psychiatric disorders and related traits. Although significant genetic correlations …
comorbid psychiatric disorders and related traits. Although significant genetic correlations …