Active ulcerative colitis (UC) is characterized by activation and infiltration of granulocytes
and monocytes/macrophages into the colonic mucosa. The infiltrated leukocytes can cause …

Background & Aims: Active ulcerative colitis (UC) is characterized by infiltration of activated
granulocytes and monocytes/macrophages (GM) within the large bowel mucosa. GM are …

Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease that appears
with varying severity. The disease is associated with activation of the immune system and …

OBJECTIVES: Granulocyte and monocyte adsorptive apheresis (GMA) has shown efficacy in
patients with active ulcerative colitis (UC). However, with routine weekly treatment, it may …

Aim: To assess safety and clinical efficacy of granulocyte and monocyte adsorptive
apheresis for distal ulcerative colitis. Methods: Granulocyte and monocyte adsorptive …

Corticosteroid therapy of ulcerative colitis (UC) is associated with frequent adverse side
effects and poor quality of life. Recently, adsorptive granulocyte and monocyte/macrophage …

BACKGROUND.: Recent evidence suggests that peripheral blood granulocytes and
monocytes/macrophages have a major role in the exacerbation of ulcerative colitis. AIMS …

Background Recently, granulocyte and monocyte adsorption apheresis (GCAP) has been
shown to be safe and effective for active ulcerative colitis (UC). We analyzed the safety and …

Recently, selective granulocytapheresis (Adacolumn) has appeared as a new treatment for
patients with inflammatory bowel disease. This study sought to determine predictors of …

Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …