A mathematical model of respiratory and biothermal dynamics in brain hypothermia treatment

L Gaohua, H Kimura - IEEE Transactions on Biomedical …, 2008 - ieeexplore.ieee.org
Brain hypothermia treatment (BHT) requires proper mechanical ventilation and therapeutic
cooling. The cooling strategy for BHT has been mainly discussed in the literature while little …

An experimental study and finite element modeling of head and neck cooling for brain hypothermia

H Li, RK Chen, Y Tang, W Meurer, AJ Shih - Journal of thermal biology, 2018 - Elsevier
Reducing brain temperature by head and neck cooling is likely to be the protective treatment
for humans when subjects to sudden cardiac arrest. This study develops the experimental …

Cooling strategies and transport theories for brain hypothermia resuscitation

J Liu - Frontiers of Energy and Power Engineering in China, 2007 - Springer
The brain is one of the most important organs in a biological body whose normal function
depends heavily on an uninterrupted delivery of oxygen. Unlike skeletal muscles that can …

Preliminary study on the oxygen consumption dynamics during brain hypothermia resuscitation

Y Ji, J Liu - 2001 Conference Proceedings of the 23rd Annual …, 2001 - ieeexplore.ieee.org
Based on the classical Pennes bioheat equation and oxygen diffusion equation, a new
coupled heat-mass transfer model for characterizing the cerebral circulatory arrest is …

Automatic air-cooling incubating system for brain hypothermia treatment

H Wakamatsu, L Gaohua - … for Acute Brain Damage: Pathomechanism and …, 2004 - Springer
A new automatic air-cooling system is proposed using a cooling incubator to replace the
manual water-cooling blanket, which has always been used for the cooling of the brain …

Automatic optimal-adaptive air-cooling system for brain hypothermia treatment

H Wakamatsu, L Gaohua - Artificial Life and Robotics, 2005 - Springer
A new automatic air-cooling system is proposed using a cooling incubator to replace the
manual water-cooling blanket which has traditionally been used to lower brain tissue …

Inducing therapeutic hypothermia via selective brain cooling: a finite element modeling analysis

L Yin, H Jiang, W Zhao, H Li - Medical & Biological Engineering & …, 2019 - Springer
Therapeutic hypothermia is a treatment method to reduce brain injuries after stroke,
especially for cerebral ischemia. This study investigates in the temperature distribution of the …

An integrated model of thermodynamic–hemodynamic–pharmacokinetic system and its application on decoupling control of intracranial temperature and pressure in …

L Gaohua, T Maekawa, H Kimura - Journal of Theoretical Biology, 2006 - Elsevier
Brain hypothermia treatment (BHT) is an intensive care characterized by simultaneous
managements of various vital signs, such as intracranial temperature (ICT) and pressure …

Theoretical simulation of temperature distribution in the brain during mild hypothermia treatment for brain injury

L Zhu, C Diao - Medical and Biological Engineering and Computing, 2001 - Springer
Mild or moderate hypothermia (> 30° C) has been proposed for clinical use as a therapeutic
option for achieving protection from cerebral ischaemia in brain injury patients. In this …

Numerical studies on the effect of lowering temperature on the oxygen transport during brain hypothermia resuscitation

Y Ji, J Liu - Computers in biology and medicine, 2002 - Elsevier
There have been arguments about the advantage and shortcoming of hypothermia on the
brain resuscitation during circulation arrest. People usually accepted that hypothermia may …