Activation of natural killer cells during microbial infections

A Horowitz, KA Stegmann, EM Riley - Frontiers in immunology, 2012 - frontiersin.org
Natural killer (NK) cells are large granular lymphocytes that express a diverse array of
germline encoded inhibitory and activating receptors for MHC Class I and Class I-like …

Natural killer cells as an initial defense against pathogens

MB Lodoen, LL Lanier - Current opinion in immunology, 2006 - Elsevier
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …

Regulation of natural killer cell activity

SE Kirwan, DN Burshtyn - Current opinion in immunology, 2007 - Elsevier
Information regarding the role of natural killer (NK) cells in the response to viruses,
intracellular bacteria and parasites continues to emerge. NK cells can directly lyse infected …

NK cells regulating T cell responses: mechanisms and outcome

J Crouse, HC Xu, PA Lang, A Oxenius - Trends in immunology, 2015 - cell.com
Natural killer (NK) cells are important innate effectors in immunity. NK cells also have a role
in the regulation of the adaptive immune response, and have been shown, in different …

Natural killer cells in immunodefense against infective agents

N Zucchini, K Crozat, T Baranek… - Expert review of anti …, 2008 - Taylor & Francis
Following the discovery of innate immune receptors, the topics of innate immunity and its
role in defense against infective agents have recently blossomed into very active research …

Recognition of infected cells by natural killer cells

LN Carayannopoulos, WM Yokoyama - Current opinion in immunology, 2004 - Elsevier
Under the influence of cytokines associated with innate immunity, natural killer (NK) cells
rapidly become activated and migrate to sites of infection. Upon contact with infected …

Natural killer cells and viral infections

AR French, WM Yokoyama - Current opinion in immunology, 2003 - Elsevier
Natural killer (NK) cells play a key role in innate host defense against viruses. Significant
progress has been made in understanding the specific response of NK cells during viral …

Natural killer cell responses to viral infection

JD Brandstadter, Y Yang - Journal of innate immunity, 2011 - karger.com
Natural killer (NK) cells, as part of the innate immune system, play a key role in host defense
against viral infections. Recent advances have indicated that NK cell activation and function …

Dynamic regulation of NK cell responsiveness

N Kadri, AK Wagner, S Ganesan, K Kärre… - Natural Killer …, 2016 - Springer
Natural killer (NK) cells deliver cytotoxic granules and immunomodulatory cytokines in
response to transformed and virally infected cells. NK cell functions are under the control of …

Successful control of viruses by NK cells–a balance of opposing forces?

AA Scalzo - Trends in microbiology, 2002 - cell.com
Natural killer (NK) cells play a crucial role in limiting the severity of diseases caused by a
range of viruses. Recent data have shown that the effector functions of NK cells can be …