Several types of calcium antagonists (CA)(verapamil, diltiazem, nifedipine and related
drugs) may be used as antihypertensives. In practice, the dihydropyridines (nifedipine and …

Characteristics of three different calcium antagonist groups: Most important calcium
antagonists used to treat cardiovascular disease belong to one of three main groups …

Calcium antagonists are effective antihypertensive drugs as monotherapy or in combination
with other drugs. Unlike beta-blockers and diuretics, there may be a closer correlation …

Abstract Comparison of first-and second-generation calcium antagonists: Despite their
diversity of structure, the first-generation calcium antagonists nifedipine, verapamil and …

Calcium ions are intimately involved in many aspects of cardiovascular function.
Modification of calcium homeostasis therefore represents a key target for pharmacological …

Calcium antagonists (CAs), introduced in cardiovascular medicine in the 1960s, should be
considered as a largely heterogeneous class of therapeutics. The diversity within this class …

A great number of calcium antagonists are available for the treatment of cardiovascular
diseases. Differences in pharmacodynamic and/or pharmacokinetic properties can be used …

Calcium channel blockers are recently developed antihypertensive drugs. In terms of
mechanisms of action, their specificity is not so well established as that of angiotensin …

There have been major advances in the understanding of the basic pharmacology of drugs
acting upon voltage-dependent and receptor-activated calcium channels using patch-clamp …

Dihydropyridinic calcium channel blockers are a subclass of antihypertensive drugs with
growing significance in the therapeutic armamentarium. Early studies in the 1990s had …