Preparation of core‐shell biodegradable microfibers for long‐term drug delivery

HH Huang, CL He, HS Wang… - Journal of Biomedical …, 2009 - Wiley Online Library
A coaxial electrospun technique to fabricate core‐shell microfibers (MFs) for drug delivery
application is described. In one‐step, Paclitaxel (PTX)‐loaded poly (l‐lactic acid‐co‐ε …

Coaxial Electrospun Poly(L‐Lactic Acid) Ultrafine Fibers for Sustained Drug Delivery

CL He, ZM Huang, XJ Han, L Liu… - … Science, Part B, 2006 - Taylor & Francis
A coaxial electrospinning technique to fabricate core‐shell ultrafine fiber mats for drug
delivery application is described in this paper. Poly (l‐lactic acid)(PLLA) and tetracycline …

Encapsulating drugs in biodegradable ultrafine fibers through co‐axial electrospinning

ZM Huang, CL He, A Yang, Y Zhang… - … Research Part A: An …, 2006 - Wiley Online Library
This article describes an electrospinning process to fabricate double‐layered ultrafine fibers.
A bioabsorbable polymer, Polycaprolactone (PCL), was used as the outer layer or the shell …

Biodegradable fibrous scaffolds composed of gelatin coated poly (ϵ‐caprolactone) prepared by coaxial electrospinning

P Zhao, H Jiang, H Pan, K Zhu… - Journal of Biomedical …, 2007 - Wiley Online Library
A facile coaxial electrospinning technique was devised to prepare biodegradable core‐shell
fibrous scaffolds with poly (ϵ‐caprolactone)(PCL) comprising the core structure and gelatin …

Biodegradable electrospun fibers for drug delivery

J Zeng, X Xu, X Chen, Q Liang, X Bian, L Yang… - Journal of controlled …, 2003 - Elsevier
The influences of surfactants and medical drugs on the diameter size and uniformity of
electrospun poly (l-lactic acid)(PLLA) fibers were examined by adding various surfactants …

PCL/PEG core/sheath fibers with controlled drug release rate fabricated on the basis of a novel combined technique

H Yu, Y Jia, C Yao, Y Lu - International journal of pharmaceutics, 2014 - Elsevier
A novel core/sheath fiber preparation method, which included the processes of blend
electrospinning to produce the core fiber and UV-induced graft polymerization to fabricate …

Ester prodrug-loaded electrospun cellulose acetate fiber mats as transdermal drug delivery systems

X Wu, CJ Branford-White, L Zhu, NP Chatterton… - Journal of Materials …, 2010 - Springer
Cellulose acetate (CA) fibers loaded with the ester prodrugs of naproxen, including methyl
ester, ethyl ester and isopropyl ester, were prepared through electrospinning using …

Biodegradable core/shell fibers by coaxial electrospinning: processing, fiber characterization, and its application in sustained drug release

C Wang, KW Yan, YD Lin, PCH Hsieh - Macromolecules, 2010 - ACS Publications
Solutions of two biodegradable polymers, that is, poly (dl-lactic acid)(PDLLA) and poly (3-
hydroxy butyrate)(PHB), were individually delivered to the inner and outer channel of a …

Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation

J Zeng, L Yang, Q Liang, X Zhang, H Guan, X Xu… - Journal of controlled …, 2005 - Elsevier
The electrospun fiber mat for drug delivery is a novel formulation with promising clinical
applications in the future. The influence of the solubility and compatibility of drugs in the …

Encapsulation and controlled release of heparin from electrospun poly (l-lactide-co-ε-caprolactone) nanofibers

Y Su, X Li, Y Liu, Q Su, MLW Qiang… - Journal of Biomaterials …, 2011 - Taylor & Francis
Poly (L-lactide-co-ε-caprolactone) nanofibers with heparin incorporated were successfully
fabricated by coaxial electrospinning. The morphologies of electrospun nanofibers were …