Nicotinic acetylcholine receptors (nAChRs) have been historically defined as ligand-gated
ion channels and function as such in the central and peripheral nervous systems. Recently …

Nicotinic acetylcholine receptors (nAChRs) are actively being investigated as therapeutic
targets for the treatment of pain and inflammation, but despite more than 30 years of …

Background: Nicotine and nicotinic acetylcholine receptors (nAChRs) have been explored
for the past three decades as targets for pain control. The aim of this review is to introduce …

Nicotinic acetylcholine receptors (nAChRs) present as many different subtypes in the
nervous and immune systems, muscles and on the cells of other organs. In the immune …

The traditional view of nicotinic acetylcholine receptors (nAChRs) is that they strictly exert
their functions via their well-known ion channel activity. With the identification of the …

The aim of the present study was to determine the impact of α 5 nicotinic acetylcholine
receptor (nAChR) subunit deletion in the mouse on the development and intensity of …

Activation of nicotinic acetylcholine receptors (nAChRs) expressed by innate immune cells
can attenuate pro-inflammatory responses. Silent nAChR agonists, which down-modulate …

Background: The nicotinic acetylcholine receptor (nAChR) gene family encodes for subunits
of acetylcholine gated ion channels. These receptors are expressed widely and have many …

α9α10 nicotinic acetylcholine receptors (nAChRs) have been identified in a variety of tissues
including lymphocytes and dorsal root ganglia; except in the case of the auditory system, the …

Neuropathic pain is a complex and debilitating syndrome for which there are few effective
pharmacological treatments. Opioid‐based medications are initially effective for acute pain …