N, N′ bis-(2-mercaptoethyl) isophthalamide (NBMI) exerts neuroprotection against lead-induced toxicity in U-87 MG cells
R Gadde, S Betharia - Archives of Toxicology, 2021 - Springer
Abstract N, N'-bis (2-mercaptoethyl) isophthalamide (NBMI) is a novel lipophilic heavy metal
chelator and thiol redox antioxidant. This study was designed to investigate the …
chelator and thiol redox antioxidant. This study was designed to investigate the …
Therapeutic Effects of Sodium Para-Aminosalicylic Acid on Cognitive Deficits and Activated ERK1/2-p90RSK/NF-κB Inflammatory Pathway in Pb-Exposed Rats
L Lu, Y Zhang, Z Li, Y Fang, L Wang, Y Zhao… - Biological trace element …, 2022 - Springer
Lead (Pb) is a toxic heavy metal and environmental pollutant that adversely affects the
nervous system. However, effective therapeutic drugs for Pb-induced neurotoxicity have yet …
nervous system. However, effective therapeutic drugs for Pb-induced neurotoxicity have yet …
Sodium para-aminosalicylic acid inhibits lead-induced neuroinflammation in brain cortex of rats by modulating SIRT1/HMGB1/NF-κB pathway
Y Zhao, J Li, Z Li, L Wang, C Gan, J Chen… - Neurochemical …, 2023 - Springer
Lead (Pb) is considered to be a major environmental pollutant and occupational health
hazard worldwide which may lead to neuroinflammation. However, an effective treatment for …
hazard worldwide which may lead to neuroinflammation. However, an effective treatment for …
Neuroprotective effect of morin on lead acetate-induced apoptosis by preventing cytochrome c translocation via regulation of Bax/Bcl-2 ratio
S Thangarajan, A Vedagiri, S Somasundaram… - Neurotoxicology and …, 2018 - Elsevier
Lead (Pb) intoxication is a prevalent type of environmental toxicity as well as minimal
amount of lead exposure is liable for neurobehavioral or perhaps intelligence defects. The …
amount of lead exposure is liable for neurobehavioral or perhaps intelligence defects. The …
Neuroprotective role of luteolin against lead acetate-induced cortical damage in rats
RS Baty, KE Hassan, KF Alsharif… - Human & …, 2020 - journals.sagepub.com
Luteolin (LUT) is a glycosylated flavonoid compound that has multiple beneficial
pharmacological and biological impacts. The current investigation was undertaken to …
pharmacological and biological impacts. The current investigation was undertaken to …
Effects of Salinomycin and Deferiprone on Lead-Induced Changes in the Mouse Brain
E Petrova, Y Gluhcheva, E Pavlova, I Vladov… - International Journal of …, 2023 - mdpi.com
Lead (Pb) is a highly toxic heavy metal that has deleterious effects on the central nervous
system. This study aimed to investigate the effects of salinomycin (Sal) and deferiprone …
system. This study aimed to investigate the effects of salinomycin (Sal) and deferiprone …
Synergistic protective effect of Betavulgaris with meso-2,3-dimercaptosuccinic acid against lead-induced neurotoxicity in male rats
NZ Shaban, SE Abd El-Kader, FAK Mogahed… - Scientific Reports, 2021 - nature.com
Lead (Pb) toxicity is one of the most prevalent causes of human neurotoxicity. The available
chelator drugs used now have many adverse effects. So, in this study, the protective role of …
chelator drugs used now have many adverse effects. So, in this study, the protective role of …
Proteomic Analysis of Protective Effects of Dl-3-n-Butylphthalide against mpp+-Induced Toxicity via downregulating P53 pathway in N2A Cells
Y Zhao, J Zhang, Y Zhang, S Li, Y Gao, C Chang… - Proteome Science, 2023 - Springer
Abstract Background Dl-3-n-butylphthalide (NBP) is an important medial therapy for acute
ischemic stroke in China. Recent studied have revealed that NBP not only rescued the loss …
ischemic stroke in China. Recent studied have revealed that NBP not only rescued the loss …
Acute exposure to lead acetate activates microglia and induces subsequent bystander neuronal death via caspase-3 activation
Lead is one of the major pollutants of environment and is highly toxic to the functioning of
central nervous system (CNS). The chronic exposure of this heavy metal is debilitating to the …
central nervous system (CNS). The chronic exposure of this heavy metal is debilitating to the …
Protective effect of puerarin on lead-induced mouse cognitive impairment via altering activities of acetyl cholinesterase, monoamine oxidase and nitric oxide synthase
CM Liu, GH Zheng, QL Ming, JM Sun… - Environmental toxicology …, 2013 - Elsevier
Puerarin (PU), a natural flavonoid, has been reported to have many benefits and medicinal
properties. The present study aimed to investigate the protective effects of puerarin on …
properties. The present study aimed to investigate the protective effects of puerarin on …