Genetic alterations and their clinical implications in DLBCL
Y Miao, LJ Medeiros, Y Li, J Li, KH Young - Nature reviews Clinical …, 2019 - nature.com
Diffuse large B cell lymphoma (DLBCL) is a highly heterogeneous lymphoid neoplasm with
variations in gene expression profiles and genetic alterations, which lead to substantial …
variations in gene expression profiles and genetic alterations, which lead to substantial …
The genetic landscape of diffuse large B-cell lymphoma
L Pasqualucci, R Dalla-Favera - Seminars in hematology, 2015 - Elsevier
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in the
western world, is an aggressive disease that remains incurable in approximately 30% of …
western world, is an aggressive disease that remains incurable in approximately 30% of …
Genetics of diffuse large B-cell lymphoma
L Pasqualucci, R Dalla-Favera - Blood, The Journal of the …, 2018 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL), the most frequent subtype of lymphoid malignancy,
remains a significant clinical challenge, as∼ 30% of patients are not cured. Over the past …
remains a significant clinical challenge, as∼ 30% of patients are not cured. Over the past …
Genetics and pathogenesis of diffuse large B-cell lymphoma
R Schmitz, GW Wright, DW Huang… - New England journal …, 2018 - Mass Medical Soc
Background Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B …
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B …
Molecular pathogenesis of diffuse large B-cell lymphoma
IS Lossos - Journal of Clinical Oncology, 2005 - ascopubs.org
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous clinicopathologic entity
accounting for 30% of non-Hodgkin's lymphomas. The pathogenesis of DLBCL is complex …
accounting for 30% of non-Hodgkin's lymphomas. The pathogenesis of DLBCL is complex …
The genetic basis of diffuse large B-cell lymphoma
L Pasqualucci - Current opinion in hematology, 2013 - journals.lww.com
The identification of genetic alterations that contribute to the malignant transformation of a B
cell into a DLBCL is helping to better understand the biology of this disease and to identify …
cell into a DLBCL is helping to better understand the biology of this disease and to identify …
[HTML][HTML] Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets
K Karube, A Enjuanes, I Dlouhy, P Jares… - Leukemia, 2018 - nature.com
Genome studies of diffuse large B-cell lymphoma (DLBCL) have revealed a large number of
somatic mutations and structural alterations. However, the clinical significance of these …
somatic mutations and structural alterations. However, the clinical significance of these …
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with recognized
variability in clinical outcome, genetic features, and cells of origin. To date, transcriptional …
variability in clinical outcome, genetic features, and cells of origin. To date, transcriptional …
[HTML][HTML] Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma
L Pedrosa, I Fernández-Miranda, D Pérez-Callejo… - Scientific reports, 2021 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease whose prognosis is
associated with clinical features, cell-of-origin and genetic aberrations. Recent integrative …
associated with clinical features, cell-of-origin and genetic aberrations. Recent integrative …
[HTML][HTML] Genetic and functional drivers of diffuse large B cell lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is
characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity …
characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity …