Defective extraembryonic angiogenesis in mice lacking LBP-1a, a member of the grainyhead family of transcription factors

V Parekh, A McEwen, V Barbour… - … and cellular biology, 2004 - Taylor & Francis
LBP-1a and CP2 are ubiquitously expressed members of the grainyhead transcription factor
family, sharing significant sequence homology, a common DNA binding motif, and …

The bHLH-Zip transcription factor Tfeb is essential for placental vascularization

E Steingrímsson, L Tessarollo, SW Reid… - …, 1998 - journals.biologists.com
Tfeb is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. In vitro
studies have shown that TFEB can bind DNA as a homodimer or as a heterodimer with three …

[HTML][HTML] The transcriptional co-repressor TLE3 regulates development of trophoblast giant cells lining maternal blood spaces in the mouse placenta

M Gasperowicz, C Surmann-Schmitt, Y Hamada… - Developmental …, 2013 - Elsevier
TLE3 is a transcriptional co-repressor that interacts with several DNA-binding repressors,
including downstream effectors of the Notch signaling pathway. We generated Tle3-deficient …

Dlx3 and GCM‐1 functionally coordinate the regulation of placental growth factor in human trophoblast‐derived cells

S Li, MS Roberson - Journal of Cellular Physiology, 2017 - Wiley Online Library
Placental growth factor (PGF) is abundantly expressed by trophoblast cells within human
placentae and is important for trophoblast development and placental vascularization …

The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis

CT Kuo, ML Veselits, KP Barton, MM Lu… - Genes & …, 1997 - genesdev.cshlp.org
The transcriptional programs that regulate blood vessel formation are largely unknown. In
this paper, we examine the role of the zinc finger transcription factor LKLF in murine blood …

Brachyury is required for elongation and vasculogenesis in the murine allantois

KE Inman, KM Downs - 2006 - journals.biologists.com
Mouse conceptuses homozygous for mutations in brachyury (T) exhibit a short, misshapen
allantois that fails to fuse with the chorion. Ultimately, mutant embryos die during mid …

The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning

D Escalante-Alcalde, L Hernandez, H Le Stunff… - 2003 - journals.biologists.com
Bioactive phospholipids, which include sphingosine-1-phosphate, lysophosphatidic acid,
ceramide and their derivatives regulate a wide variety of cellular functions in culture such as …

[HTML][HTML] Placental angiogenesis in mammals: a review of the regulatory effects of signaling pathways and functional nutrients

Z Huang, S Huang, T Song, Y Yin, C Tan - Advances in Nutrition, 2021 - Elsevier
Normal placental development and proper angiogenesis are essential for fetal growth
during pregnancy. Angiogenesis involves the regulatory action of many angiogenic factors …

G9a controls placental vascular maturation by activating the Notch Pathway

L Chi, A Ahmed, AR Roy, S Vuong, LS Cahill… - …, 2017 - journals.biologists.com
Defective fetoplacental vascular maturation causes intrauterine growth restriction (IUGR). A
transcriptional switch initiates placental maturation, during which blood vessels elongate …

Identification and characterization of Grainyhead‐like epithelial transactivator (GET‐1), a novel mammalian Grainyhead‐like factor

EI Kudryavtseva, TM Sugihara, N Wang… - … Dynamics: An Official …, 2003 - Wiley Online Library
LMO‐4 is an LIM‐only factor that is highly expressed in many epithelial cells, including those
of the epidermis and hair follicles. Because LMOs may function by interacting with DNA …