[HTML][HTML] Oncogenomic changes in pancreatic cancer and their detection in stool

H Sammallahti, VK Sarhadi, A Kokkola, R Ghanbari… - Biomolecules, 2022 - mdpi.com
Pancreatic cancer (PC) is an aggressive malignancy with a dismal prognosis. To improve
patient survival, the development of screening methods for early diagnosis is pivotal …

[HTML][HTML] Integrative genomic and functional profiling of the pancreatic cancer genome

AH Shain, K Salari, CP Giacomini, JR Pollack - BMC genomics, 2013 - Springer
Background Pancreatic cancer is a deadly disease with a five-year survival of less than 5%.
A better understanding of the underlying biology may suggest novel therapeutic targets …

[HTML][HTML] Microbiota alterations and their association with oncogenomic changes in pancreatic cancer patients

H Sammallahti, A Kokkola, S Rezasoltani… - International Journal of …, 2021 - mdpi.com
Pancreatic cancer (PC) is an aggressive disease with a high mortality and poor prognosis.
The human microbiome is a key factor in many malignancies, having the ability to alter host …

[HTML][HTML] Omics approaches in pancreatic adenocarcinoma

I González-Borja, A Viúdez, S Goñi, E Santamaria… - Cancers, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma, which represents 80% of pancreatic cancers, is mainly
diagnosed when treatment with curative intent is not possible. Consequently, the overall five …

Integrated Analysis of Multi-Omics Data to Identify Prognostic Genes for Pancreatic Cancer

F Jiang, X Huang, F Zhang, J Pan, J Wang… - DNA and Cell …, 2022 - liebertpub.com
Pancreatic cancer (PC) is a common cause of cancer-related deaths. Current research
shows that prognostic biomarkers play a key role in the treatment of PC. This study aimed to …

Microbiome alterations in pancreatic cancer: new insights and potential clinical implications

D Ansari, H Ibrahim, R Andersson - Scandinavian Journal of …, 2024 - Taylor & Francis
Pancreatic cancer is a formidable disease and represents a major public health problem.
Globally, around 496,000 cases of pancreatic cancer are diagnosed each year, with almost …

[HTML][HTML] Fecal microbiome signatures of pancreatic cancer patients

E Half, N Keren, L Reshef, T Dorfman, I Lachter… - Scientific reports, 2019 - nature.com
Pancreatic cancer (PC) is a leading cause of cancer-related death in developed countries,
and since most patients have incurable disease at the time of diagnosis, developing a …

[HTML][HTML] Integrative analysis reveals clinically relevant molecular fingerprints in pancreatic cancer

L Song, S Qi, W Hu, Z Fang, D Yu, T Liu, J Wu… - … Therapy-Nucleic Acids, 2021 - cell.com
Pancreatic cancer is a highly aggressive cancer with an exceedingly low rate of response to
treatments, which calls for comprehensive molecular characterization of pancreatic cancer …

Pancreatic Cancer Database: an integrative resource for pancreatic cancer

JK Thomas, MS Kim, L Balakrishnan… - Cancer biology & …, 2014 - Taylor & Francis
Pancreatic cancer is the fourth leading cause of cancer-related death in the world. The
etiology of pancreatic cancer is heterogeneous with a wide range of alterations that have …

[HTML][HTML] Integrated single-cell multiomics analysis reveals novel candidate markers for prognosis in human pancreatic ductal adenocarcinoma

X Fan, P Lu, H Wang, S Bian, X Wu, Y Zhang, Y Liu… - Cell Discovery, 2022 - nature.com
The epigenomic abnormality of pancreatic ductal adenocarcinoma (PDAC) has rarely been
investigated due to its strong heterogeneity. Here, we used single-cell multiomics …