Abstract The hyaluronan synthase 2 (HAS2)-hyaluronic acid (HA)-CD44-Caspase-3
pathway is involved in ovarian granulosa cell (GC) functions in mammals. HAS2 is a key …

Background MiRNAs play important roles in the development of ovarian cancer, activation of
primitive follicles, follicular development, oocyte maturation and ovulation. In the present …

Granulosa cell (GC) apoptosis has been shown to be involved in follicular atresia, which is a
degenerative process in ovarian follicles of mammals. However, the mechanism underlying …

This study embarked on the assessment regarding the function and mechanism of miR-
520h/IL6R axis in polycystic ovary syndrome (PCOS). Specifically, we analyzed the …

Granulosa cells (GCs) are essential somatic cells in the ovary and play an important role in
folliculogenesis. Brain-derived neurotropic factor (BDNF) and the TGF-β pathway have been …

Chicken atrophic ovaries have decreased volume and are indicative of ovarian failure,
presence of a tumor, or interrupted ovarian blood supply. Ovarian tumor is accompanied by …

Abstract Porcine 17-hydroxysteroid dehydrogenase type 14 (HSD17B14) and FSH reporter
(FSHR) genes play important roles in the metabolism of steroid hormones and the apoptosis …

Abstract microRNA-22 (miR-22) is a brain-enriched regulatory gene which has been
reported to be involved in the development of cancers. The Notch signaling pathway exerts …

Ovarian cancer (OC) is xenogeneic that is influenced by many generated factors related to
epigenetic factors to accelerate tumor metastasis. This study was conducted with the …

In mammals, follicular atresia can be partially triggered by granulosa cell apoptosis.
However, very little is known about the functions of miRNAs in granulosa cell apoptosis. We …